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Aggressive verrucous carcinoma of the paranasal sinuses invading the orbit: case report and literature review

Published online by Cambridge University Press:  11 August 2009

J Yiotakis ,
T Vamvakidis ,
E Iakovou  and
L Manolopoulos
J Yiotakis
Affiliation:
Otorhinolaryngology Department, Athens University, Ippokration General Hospital, Greece
T Vamvakidis*
Affiliation:
Otorhinolaryngology Department, Athens University, Ippokration General Hospital, Greece
E Iakovou
Affiliation:
Otorhinolaryngology Department, Athens University, Ippokration General Hospital, Greece
L Manolopoulos
Affiliation:
Otorhinolaryngology Department, Athens University, Ippokration General Hospital, Greece
*
Address for correspondence: Dr Theodore Vamvakidis, 114 Vas Sofias Av, Athens 11527, Greece. Fax: +30 210 6144290 E-mail: theodorevamb@hotmail.com
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Abstract

Introduction:

Verrucous carcinoma is a variant of well differentiated squamous cell carcinoma characterised by an exophytic, warty growth which is slowly but locally invasive and which can cause extensive local destruction if left untreated.

Case report:

We report the first known case of veruccous carcinoma of the paranasal sinuses with rapid orbital invasion. A 58-year-old man presented with right-sided nasal obstruction, a huge right intranasal lesion, intractable dacryocystitis and cutaneous involvement of the nasolacrimal sac region. The tumour was partially removed using an endoscopic transnasal approach. Post-operatively, and while waiting for the histological result, the patient developed signs of rapid invasion of the orbit, with uniocular visual acuity deficit. He underwent combined radiochemotherapy, with a moderate response.

Conclusion:

Knowledge of the potentially aggressive nature of verrucous carcinoma may be helpful in early management of intraorbital invasion and salvaging of the eye.

Keywords

Nasal CavityOrbitVerrucous CarcinomaHead and Neck Neoplasms
Type
Online Only Clinical Records
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 11 , November 2009 , e23
Copyright
Copyright © JLO (1984) Limited 2009

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