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Angioedema of the airway: an unusual case

Published online by Cambridge University Press:  31 May 2007

A J Roper ,
A Farragher ,
J J Homer  and
M Helbert
A J Roper*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Immunology, Manchester Royal Infirmary, UK.
A Farragher
Affiliation:
Immunology, Manchester Royal Infirmary, UK
J J Homer
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Immunology, Manchester Royal Infirmary, UK.
M Helbert
Affiliation:
Immunology, Manchester Royal Infirmary, UK
*
Address for correspondence: Miss A J Roper, 52 Goulden Road, West Didsbury, Manchester M20 4YF, UK. E-mail: ajroper@doctors.org.uk
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Abstract

We report a case of angioedema caused by angiotensin-converting enzyme inhibitor and topical lignocaine spray, administered during nasendoscopy.

Angioedema induced by angiotensin-converting enzyme inhibitors is a rare but well known entity. Allergy to topical lignocaine has been acknowledged as a rare phenomenon when used for dental surgery and for skin anaesthesia, but it has not previously been reported after topical administration prior to nasendoscopy. In the reported case, our patient was unfortunate enough to be allergic to both lisinopril and lignocaine. The result was life-threatening airway obstruction, and the continued use of lignocaine spray sustained the laryngeal oedema. We advise that patients are asked about any and every allergy – specifically, any previous problems with dental procedures – before administration of local anaesthetic spray to the upper aerodigestive tract.

Keywords

AngioedemaAngioneurotic EdemaAngiotensin Converting Enzyme InhibitorLocal Anesthetic Allergy
Type
Online Only Clinical Records
Information
The Journal of Laryngology & Otology , Volume 121 , Issue 8 , August 2007 , E11
Copyright
Copyright © JLO (1984) Limited 2007

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