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Assessment of nasal mucociliary activity in patients with Behçet's disease

Published online by Cambridge University Press:  04 February 2016

I Ozbay ,
C Kucur ,
F Temİzturk ,
Y Ozkan ,
C Kahraman  and
F Oghan
I Ozbay*
Affiliation:
Department of ORL, Dumlupinar University, Kutahya, Turkey
C Kucur
Affiliation:
Department of ORL, Dumlupinar University, Kutahya, Turkey
F Temİzturk
Affiliation:
Department of Physical Therapy and Rehabilitation, Dumlupinar University, Kutahya, Turkey
Y Ozkan
Affiliation:
Department of Physical Therapy and Rehabilitation, Dumlupinar University, Kutahya, Turkey
C Kahraman
Affiliation:
Department of Internal Medicine, Dumlupinar University, Kutahya, Turkey
F Oghan
Affiliation:
Department of ORL, Dumlupinar University, Kutahya, Turkey
*
Address for correspondence: Dr Isa Ozbay, Department of Otolaryngology, Medicine Faculty of Dumlupinar University, Kutahya, Turkey Fax: +90 274 231 6673 E-mail: isaozbay@gmail.com
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Abstract

Objective:

To investigate nasal mucociliary clearance in patients with Behçet's disease.

Methods:

Thirty patients with Behçet's disease, diagnosed on the basis of criteria defined by the International Study Group for Behçet's Disease, and 30 healthy individuals were recruited. In both groups, individuals with conditions that could affect nasal mucociliary clearance were excluded. Nasal mucociliary clearance time was evaluated using saccharin tests. The time between placement of a saccharin tablet and the tasting of the saccharin was measured and recorded as the saccharin clearance time.

Results:

The mean nasal mucociliary clearance time was significantly longer in the Behçet's disease patients than in the control subjects (p < 0.001). Furthermore, there was a positive correlation between Behçet's disease duration and nasal mucociliary clearance time (p < 0.001, r = 0.882).

Conclusion:

The results suggest that nasal mucociliary clearance time is longer in Behçet's disease patients than in control subjects, and is positively correlated with disease duration.

Keywords

Nasal MucosaBehçet DiseaseSaccharin
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 130 , Issue 4 , April 2016 , pp. 348 - 351
Copyright
Copyright © JLO (1984) Limited 2016 

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