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Audio-vestibular findings in meningioma of the cerebello-pontine angle: a retrospective review

Published online by Cambridge University Press:  29 June 2007

David M. Baguley ,
Graham J. Beynon ,
Philip L. Greyf ,
David G. Hardya  and
David A. Moffat
David M. Baguley*
Affiliation:
Department of Audiology, Addenbrooke's Hospital, Cambridge, UK
Graham J. Beynon
Affiliation:
Department of Audiology, Addenbrooke's Hospital, Cambridge, UK
Philip L. Greyf
Affiliation:
Departments of Otolaryngology, Addenbrooke's Hospital, Cambridge, UK ENT Department, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
David G. Hardya
Affiliation:
Departments of Neurosurgeryt, Addenbrooke's Hospital, Cambridge, UK
David A. Moffat
Affiliation:
Departments of Otolaryngology, Addenbrooke's Hospital, Cambridge, UK
*
Address for correspondence: David M. Baguley, M.Sc., M.B.A., Department of Audiology (94), Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ. Fax: 01223 217559 e-mail: dmb29@cam.ac.uk
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Abstract

The aim of this study was the determination of the incidence of symptoms of audio-vestibular dysfunction and of abnormalities on audio-vestibular testing in patients found to have a unilateral meningioma of the cerebello-pontine angle (CPA). The case notes of 25 patients diagnosed with unilateral, sporadic and histologically proven CPA meningioma were retrospectively reviewed. The age range of this series was 31–71 years, with a mean age of 50 years. Two patients were male (eight per cent) and 23 were female (92 per cent). The mean length of history was 44.7 months. The distribution of tumour size was skewed toward larger tumours, with 15 cases (60 per cent) having tumours with a maximum diameter greater than 3.5 cm on imaging. Pure tone audiometry was normal in five cases (20 per cent), and no patients exhibited the high frequency sensorineural hearing loss that is characteristic of vestibular schwannoma. Speech audiometry was normal in 50 per cent of cases. Caloric testing was abnormal in 77 per cent of the 18 cases tested, whilst auditory brainstem responses (ABR) were abnormal in 100 per cent of the 18 cases who had sufficient hearing for this test to be possible. The presence of normal audiometry in patients with a proven CPA lesion indicates that, if in a protocol for investigation, asymmetry of hearing is mandatory then some pathology will be missed. Any suspicion of a CPA lesion warrants investigation even in the absence of hearing loss.

The investigation of choice for the identification of CPA lesions has become magnetic resonance imaging (MRI). If this technique is not available then this study indicates that ABR is a suitable and sensitive investigation. It should be borne in mind however that the data in this study has been derived from a series of predominantly large tumours, and the sensitivity of ABR to smaller CPA meningiomata may fall, as is the case for vestibular schwannoma.

Keywords

MeningiomaCerebellopontine angleAudiologyDiagnosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 11 , November 1997 , pp. 1022 - 1026
Copyright
Copyright © JLO (1984) Limited 1997

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