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Auditory and vestibular hair cell stereocilia: relationship between functionality and inner ear disease

Published online by Cambridge University Press:  21 July 2011

R R Ciuman
R R Ciuman*
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Marienhospital Gelsenkirchen, Germany
*
Address for correspondence: Dr Raphael R Ciuman, Uranusbogen 15, 45478 Mülheim, Germany E-mail: ciuman.raphael@cityweb.de
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Abstract

The stereocilia of the inner ear are unique cellular structures which correlate anatomically with distinct cochlear functions, including mechanoelectrical transduction, cochlear amplification, adaptation, frequency selectivity and tuning. Their function is impaired by inner ear stressors, by various types of hereditary deafness, syndromic hearing loss and inner ear disease (e.g. Ménière's disease). The anatomical and physiological characteristics of stereocilia are discussed in relation to inner ear malfunctions.

Keywords

CiliaBiochemistryCochleaPhysiologyPathologyUsher SyndromeHearing Loss
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 10 , October 2011 , pp. 991 - 1003
Copyright
Copyright © JLO (1984) Limited 2011

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