Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-11T05:52:35.123Z Has data issue: false hasContentIssue false
  • English
  • Français

Beta adrenoceptors in human nasal mucosa

Published online by Cambridge University Press:  29 June 2007

C. J. Woodhead  and
A. J. Nimmo
C. J. Woodhead*
Affiliation:
Department of Otolarynology, Leeds General Infirmary.
A. J. Nimmo
Affiliation:
Department of Physiology, Leeds University.
*
Mr C. J. Woodhead, Department of Otolaryngology, St James University Hospital, Beckett Street, Leeds.
Get access Rights & Permissions [Opens in a new window]

Abstract

The significance of the beta adrenergic system in the nasal mucosa isunclear. The authors have used the technique of autoradiography to localize and classify beta adrenoceptors in human nasal mucosa. The receptors have been found to beexclusively of thebeta-2 subtype and the highest density is found in the glandularducts. It is suggested that the beta-adrenergic system may have a physiologically important role in controlling the electrolyte composition of nasal secretions.

Keywords

AdrenoreceptorsNasal mucosa
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 8 , August 1991 , pp. 632 - 634
Copyright
Copyright © JLO (1984) Limited 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Andersson, K. E., Bende, M. (1984) Adrenoceptors in the control of human nasal mucosal blood flow. Annals of Otology, Rhinology and Laryngology, 93: 179–182.CrossRefGoogle ScholarPubMed
Borum, P., Larsen, F. S. (1987) Seasonal allergic rhinitistreated with a beta-2 adrenostimulant. Allergy, 42: 141–145.CrossRefGoogle Scholar
Carstairs, J. R., Nimmo, A. J., Barnes, P. J. (1985) Autoradiographic visualization of beta-adrenoceptor subtypes in human lung. American Review of Respiratory Diseases, 132: 541–547.Google ScholarPubMed
Hall, L. J., Jackson, R. T. (1968) Effects of alpha andbetaadrenergic agonists on nasal blood flow. Annals of Otology, Rhinologyand Laryngology, 77: 1120–1130.CrossRefGoogle ScholarPubMed
Konno, A., Terada, N., Okamoto, Y. (1987) Responses of resistanceand capacitance vessels in human nasal mucosa to betareceptoragonists. Journal of Otorhinolaryngology and Related Specialties, 49: 206–213.CrossRefGoogle Scholar
Levin, R. J., Sebkhi, A. (1989) Electrogenic ion secretionof ratendometrium in vitro–action of adrenaline and A23187. Journal of Physiology, 416: 37.Google Scholar
Malm, L. (1974) Beta-adrenergic receptors in the vessels of the catnasal mucosa. Ada Otolaryngologica, 78: 242–246.CrossRefGoogle ScholarPubMed
Van Megen, Y. J. B., Van Ratingen, C. J. B. M., Klaassen, A. B. M., Rodrigues de Miranda, J. F., Van Ginneken, C. A. M., van denBroek, P. (1988) Demonstration of beta-adrenergic receptors in rat nasal glands by an in vitro autoradiographic technique. Neuroscience Letters, 90: 75–77.CrossRefGoogle ScholarPubMed
Watanabe, K., Harada, H. (1990) Beta-adrenoceptor control of peroxidase synthesis in nasal glands. Annals of Otology, Rhinology, and Laryngology, 99: 581–585.CrossRefGoogle ScholarPubMed