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Correlation between radiological images and pathological results in supraglottic cancer

Published online by Cambridge University Press:  03 March 2008

J W Kim ,
S-Y Yoon ,
I-S Park ,
S-W Park  and
Y-M Kim
J W Kim
Affiliation:
Department of Otorhinolaryngology, Inha University, College of Medicine, Incheon, South Korea
S-Y Yoon
Affiliation:
Department of Otorhinolaryngology, Inha University, College of Medicine, Incheon, South Korea
I-S Park
Affiliation:
Department of Pathology, Inha University, College of Medicine, Incheon, South Korea
S-W Park
Affiliation:
Department of Radiology, Inha University, College of Medicine, Incheon, South Korea
Y-M Kim*
Affiliation:
Department of Otorhinolaryngology, Inha University, College of Medicine, Incheon, South Korea
*
Address for correspondence: Dr Young-Mo Kim, Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine, 3-Ga Shinheung-dong, Jung-Gu, Incheon 400-711, South Korea. Fax: 82-32-890-3580 E-mail: ymk416@inha.ac.kr
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Abstract

Introduction:

Radiological imaging plays an indispensable, complementary role to endoscopy in the pre-therapeutic assessment of laryngeal cancer. We evaluated the reliability of radiological imaging in determining the extent of cancer and surgical resection, by comparing the results of pre-operative computed tomography and magnetic resonance imaging with those for post-operative pathological analysis.

Material and methods:

Twenty-nine patients who had undergone laryngeal cancer surgery with a diagnosis of supraglottic cancer were reviewed. Imaging reliability was assessed for separate subunit regions of the supraglottic area, the glottic area and the cartilage.

Results:

The false diagnosis rate for all subunits was 25 per cent. The rate of false diagnosis associated with overstaging was 21 per cent. The rate of false diagnosis associated with understaging was 4 per cent.

Conclusion:

In order to give the best chance of laryngeal preservation, especially in the case of false positive laryngeal subsites, computed tomography and magnetic resonance imaging should be combined with pre-operative endoscopy and intra-operative frozen section diagnosis.

Keywords

Larynx NeoplasmsComputed TomographyMagnetic Resonance ImagingNeoplasm Staging
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 11 , November 2008 , pp. 1224 - 1229
Copyright
Copyright © JLO (1984) Limited 2008

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