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Diagnostic value of three-dimensional magnetic resonance imaging of inner ear after intratympanic gadolinium injection, and clinical application of magnetic resonance imaging scoring system in patients with delayed endolymphatic hydrops

Published online by Cambridge University Press:  20 December 2013

X Gu ,
Z-M Fang ,
Y Liu ,
S-L Lin ,
B Han ,
R Zhang  and
X Chen
X Gu
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
Z-M Fang
Affiliation:
Department of Radiology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
Y Liu
Affiliation:
Department of Radiology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
S-L Lin
Affiliation:
Department of Audiology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
B Han
Affiliation:
Computer Teaching and Research Section, Dalian Medical University, Liaoning Province, People's Republic of China
R Zhang
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
X Chen*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
*
Address for correspondence: Dr X Chen, Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, 20 Cha Zhong Road, Tai Jiang District, Fuzhou 350005, Fujian Province, People's Republic of China E-mail: chenxi3518@sina.com
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Abstract

Objective:

Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging of the inner ear after intratympanic injection of gadolinium, together with magnetic resonance imaging scoring of the perilymphatic space, were used to investigate the positive identification rate of hydrops and determine the technique's diagnostic value for delayed endolymphatic hydrops.

Methods:

Twenty-five patients with delayed endolymphatic hydrops underwent pure tone audiometry, bithermal caloric testing, vestibular-evoked myogenic potential testing and three-dimensional magnetic resonance imaging of the inner ear after bilateral intratympanic injection of gadolinium. The perilymphatic space of the scanned images was analysed to investigate the positive identification rate of endolymphatic hydrops.

Results:

According to the magnetic resonance imaging scoring of the perilymphatic space and the diagnostic standard, 84 per cent of the patients examined had endolymphatic hydrops. In comparison, the positive identification rates for vestibular-evoked myogenic potential and bithermal caloric testing were 52 per cent and 72 per cent respectively.

Conclusion:

Three-dimensional magnetic resonance imaging after intratympanic injection of gadolinium is valuable in the diagnosis of delayed endolymphatic hydrops and its classification. The perilymphatic space scoring system improved the diagnostic accuracy of magnetic resonance imaging.

Keywords

Endolymphatic HydropsMRI ScansGadoliniumEar, InnerPathologyDiagnosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 1 , January 2014 , pp. 53 - 59
Copyright
Copyright © JLO (1984) Limited 2013 

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References

1Nadol, JB Jr, Weiss, AD, Parker, SW. Vertigo of delayed onset after sudden deafness. Ann Otol Rhinol Laryngol 1975;84:841–6Google Scholar
2Schuknecht, HF. Delayed endolymphatic hydrops. Ann Otol Rhinol Laryngol 1978;87:743–8CrossRefGoogle ScholarPubMed
3Nakashima, T, Naganawa, S, Sugiura, M, Teranishi, M, Sone, M, Hayashi, H et al. Visualization of endolymphatic hydrops in patient with Meniere's disease. Laryngoscope 2007;117:415–20CrossRefGoogle ScholarPubMed
4Fang, Z-M, Chen, X, Gu, X, Liu, Y, Zhang, R, Cao, D-R et al. A new magnetic resonance imaging scoring system for perilymphatic space appearance after intratympanic gadolinium injection, and its clinical application. J Laryngol Otol 2012;126:454–9Google Scholar
5Huang, X-Z, Wang, J-B, Kong, W-J. Practice of Otorhinolaryngology-Head and Neck Surgery, 2nd edn.Beijing: People's Medical Publishing House, 2008;1005–6Google Scholar
6Zhou, N, Wu, ZM, Zhang, SZ, Guo, WW, Yu, LM, Yang, WY et al. Characteristics of the response of vestibular evoked myogenic potentials to different stimulus modes [in Chinese]. Zhonghua Er Bi Yan Hou Ke Za Zhi 2004;39:483–5Google Scholar
7Kamei, T. Delayed endolymphatic hydrops as a clinical entity. Int Tinnitus J 2004;10:137–43Google Scholar
8Fukuoka, H, Tsukada, K, Miyagawa, M, Oguchi, T, Takumi, Y, Sugiura, M et al. Semi-quantitative evaluation of endolymphatic hydrops by bilateral intratympanic gadolinium-based contrast agent (GBCA) administration with MRI for Meniere's disease. Acta Otolaryngol 2010;130:10–16CrossRefGoogle ScholarPubMed
9Fiorino, F, Pizzini, FB, Beltramello, A, Barbieri, F. MRI performed after intratympanic gadolinium administration in patients with Meniere's disease: correlation with symptoms and signs. Eur Arch Otorhinolaryngol 2011;268:181–7Google Scholar
10Campbell, KC, Harker, LA, Abbas, PJ. Interpretation of electrocochleography in Meniere's disease and normal subjects. Ann Otol Rhinol Laryngol 1992;101:496–500Google Scholar
11Ferraro, JA, Arenberg, IK, Hassanein, RS. Electrocochleography and symptoms of inner ear dysfunction. Arch Otolaryngol 1985;111:71–4Google Scholar
12Wang, Z, Shao, X, Zhi, B, Yan, W, Lin, Y. Influence of the hearing loss level and auditory sensation curve type on click evoked SP/AP amplitude ratio in Meniere's disease [in Chinese]. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2001;15:446–9Google ScholarPubMed
13Dumas, G, Lavieille, JP, Schmerber, S. Vibratory test and head shaking test and caloric test: a series of 87 patients [in French]. Ann Otolaryngol Chir Cervicofac 2004;121:22–32CrossRefGoogle ScholarPubMed
14Young, YH, Huang, TW, Cheng, PW. Vestibular evoked myogenic potentials in delayed endolymphatic hydrops. Laryngoscope 2002;112:1623–6CrossRefGoogle ScholarPubMed
15Ban, JH, Lee, JK, Jin, SM, Lee, KC. Glycerol pure tone audiometry and glycerol vestibular evoked myogenic potential: representing specific status of endolymphatic hydrops in the inner ear. Eur Arch Otorhinolaryngol 2007;264:1275–81Google Scholar
16Egami, N, Ushio, M, Yamasoba, T, Murofushi, T, Iwasaki, S. Indication of the side of delayed endolymphatic hydrops by vestibular evoked myogenic potential and caloric test. ORL J Otorhinolaryngol Relat Spec 2010;72:242–6CrossRefGoogle ScholarPubMed