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The evaluation of nasal mucociliary clearance in patients with Helicobacter pylori infection

Published online by Cambridge University Press:  06 February 2019

S Üstün Bezgin ,
T Çakabay ,
K Irak ,
M Koçyiğit ,
B Serin Keskineğe  and
S Giran Örtekin
S Üstün Bezgin*
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
T Çakabay
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
K Irak
Affiliation:
Department of Gastroenterology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
M Koçyiğit
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
B Serin Keskineğe
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
S Giran Örtekin
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
*
Author for correspondence: Dr Selin Üstün Bezgin, Otorhinolaryngology Department, Kanuni Sultan Süleyman Education and Research Hospital, Atakent mahallesi, Turgut Özal caddesi No: 1, 34303, Altınşehir, Küçükçekmece, Istanbul, Turkey E-mail: drselinustun@gmail.com Fax: +90 212 5714790
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Abstract

Objective

This study aimed to examine nasal mucociliary clearance time in patients with Helicobacter pylori infection.

Methods

Fifty patients who were newly diagnosed with H pylori infection using gastric biopsy in the gastroenterology out-patient clinic, and 50 age- and gender-matched healthy adults who were admitted to the otorhinolaryngology out-patient clinic, were included in this study. After an otorhinolaryngological examination (anterior rhinoscopy and nasal endoscopic examination), the nasal mucociliary clearance time of each subject was calculated using the saccharine test.

Results

The mean mucociliary clearance time was 06:29 ± 3:31 minutes (range, 00:55–15:19 minutes) in the control group and 10:12 ± 06:09 minutes (range, 01:28–32:00 minutes) in the study group. Comparisons of the two groups revealed a statistically significant difference (p = 0.002).

Conclusion

Nasal mucociliary clearance time was significantly increased in patients with H pylori infection. The results suggest that H pylori infection may have an unfavourable effect on nasal mucociliary clearance.

Keywords

Mucociliary ClearanceHelicobacter PyloriSaccharine
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 3 , March 2019 , pp. 220 - 223
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Dr S Ü Bezgin takes responsibility for the integrity of the content of the paper

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