Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-13T00:45:30.501Z Has data issue: false hasContentIssue false

Framingham risk score is associated with hearing outcomes in patients with idiopathic sudden sensorineural hearing loss

Published online by Cambridge University Press:  19 May 2020

Y-S Chang
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
S Park
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
M K Lee
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
Y C Rah
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
J Choi*
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
*
Author for correspondence: Dr June Choi, Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, 123, Jeokgeum-ro (Gojan-dong), Danwon-gu, Ansan-si, Gyeonggi-do15355, Republic of Korea E-mail: mednlaw@korea.ac.kr Fax: +81 31 412 5174

Abstract

Objective

To assess the Framingham risk score as a prognostic tool for idiopathic sudden sensorineural hearing loss patients.

Methods

Medical records were reviewed for unilateral idiopathic sudden sensorineural hearing loss patients between January 2010 and October 2017. The 10-year risk of developing cardiovascular disease was calculated. Patients were subdivided into groups: group 1 – Framingham risk score of less than 10 per cent (n = 28); group 2 – score of 10 to less than 20 per cent (n = 6); and group 3 – score of 20 per cent or higher (n = 5).

Results

Initial pure tone average and Framingham risk score were not significantly associated (p = 0.32). Thirteen patients in group 1 recovered completely (46.4 per cent), but none in groups 2 and 3 showed complete recovery. Initial pure tone average and Framingham risk score were significantly associated in multivariable linear regression analysis (R2 = 0.36). The regression coefficient was 0.33 (p = 0.003) for initial pure tone average and −0.67 (p = 0.005) for Framingham risk score.

Conclusion

Framingham risk score may be useful in predicting outcomes for idiopathic sudden sensorineural hearing loss patients, as those with a higher score showed poorer hearing recovery.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited, 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Dr J Choi takes responsibility for the integrity of the content of the paper

Presented at the International Congress of Otorhinolaryngology – Head and Neck Surgery (‘ICORL-HNS’) in conjunction with 93rd Annual Congress of Korean Society of Otorhinolaryngology – Head and Neck Surgery, 25–28 April 2019, Seoul, Korea.

References

Wilson, WR, Byl, FM, Laird, N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol 1980;106:772–610.1001/archotol.1980.00790360050013CrossRefGoogle ScholarPubMed
Wu, CS, Lin, HC, Chao, PZ. Sudden sensorineural hearing loss: evidence from Taiwan. Audiol Neurootol 2006;11:151–610.1159/000091198CrossRefGoogle ScholarPubMed
Nosrati-Zarenoe, R, Arlinger, S, Hultcrantz, E. Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national database. Acta Otolaryngol 2007;127:1168–7510.1080/00016480701242477CrossRefGoogle ScholarPubMed
Byl, FM Jr. Sudden hearing loss: eight years' experience and suggested prognostic table. Laryngoscope 1984;94:647–6110.1288/00005537-198405000-00014CrossRefGoogle ScholarPubMed
Chau, JK, Lin, JR, Atashband, S, Irvine, RA, Westerberg, BD. Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope 2010;120:1011–21Google ScholarPubMed
Huy, PT, Sauvaget, E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol 2005;26:89690210.1097/01.mao.0000185071.35328.6dCrossRefGoogle Scholar
Narozny, W, Kuczkowski, J, Kot, J, Stankiewicz, C, Sicko, Z, Mikaszewski, B. Prognostic factors in sudden sensorineural hearing loss: our experience and a review of the literature. Ann Otol Rhinol Laryngol 2006;115:553–810.1177/000348940611500710CrossRefGoogle Scholar
Suzuki, H, Mori, T, Hashida, K, Shibata, M, Nguyen, KH, Wakasugi, T et al. Prediction model for hearing outcome in patients with idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 2011;268:49750010.1007/s00405-010-1400-2CrossRefGoogle ScholarPubMed
Cvorovic, L, Deric, D, Probst, R, Hegemann, S. Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss. Otol Neurotol 2008;29:464–910.1097/MAO.0b013e31816fdcb4CrossRefGoogle ScholarPubMed
Kuhn, M, Heman-Ackah, SE, Shaikh, JA, Roehm, PC. Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif 2011;15:9110510.1177/1084713811408349CrossRefGoogle Scholar
Aimoni, C, Bianchini, C, Borin, M, Ciorba, A, Fellin, R, Martini, A et al. Diabetes, cardiovascular risk factors and idiopathic sudden sensorineural hearing loss: a case-control study. Audiol Neurootol 2010;15:111–1510.1159/000231636CrossRefGoogle ScholarPubMed
Marcucci, R, Alessandrello Liotta, A, Cellai, AP, Rogolino, A, Berloco, P, Leprini, E et al. Cardiovascular and thrombophilic risk factors for idiopathic sudden sensorineural hearing loss. J Thromb Haemost 2005;3:929–3410.1111/j.1538-7836.2005.01310.xCrossRefGoogle ScholarPubMed
Fukui, M, Kitagawa, Y, Nakamura, N, Kadono, M, Mogami, S, Ohnishi, M et al. Idiopathic sudden hearing loss in patients with type 2 diabetes. Diabetes Res Clin Pract 2004;63:205–1110.1016/j.diabres.2003.09.013CrossRefGoogle ScholarPubMed
Chang, Y-S, Choi, JE, Ahn, J, Ryu, N-G, Moon, IJ, Hong, SH et al. Framingham risk score as a prognostic predictor of sudden sensorineural hearing loss: a preliminary study. Ann Otol Rhinol Laryngol 2017;126:382–710.1177/0003489417694910CrossRefGoogle ScholarPubMed
Bulğurcu, S, Şahin, B, Akgül, G, Arslan, İB, Çukurova, İ. The effects of prognostic factors in idiopathic sudden hearing loss. Int Arch Otorhinolaryngol 2018;22:33–7Google ScholarPubMed
Lee, HS, Lee, YJ, Kang, BS, Lee, BD, Lee, JS. A clinical analysis of sudden sensorineural hearing loss cases. Korean J Audiol 2014;18:697510.7874/kja.2014.18.2.69CrossRefGoogle ScholarPubMed
D'Agostino, RB Sr, Vasan, RS, Pencina, MJ, Wolf, PA, Cobain, M, Massaro, JM et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008;117:743–5310.1161/CIRCULATIONAHA.107.699579CrossRefGoogle ScholarPubMed
Ho, KK, Pinsky, JL, Kannel, WB, Levy, D. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993;22(4 suppl A):613A10.1016/0735-1097(93)90455-ACrossRefGoogle ScholarPubMed
Wilson, PW, D'Agostino, RB, Levy, D, Belanger, AM, Silbershatz, H, Kannel, WB. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837–4710.1161/01.CIR.97.18.1837CrossRefGoogle ScholarPubMed
Siegel, LG. The treatment of idiopathic sudden sensorineural hearing loss. Otolaryngol Clin North Am 1975;8:467–7310.1016/S0030-6665(20)32783-3CrossRefGoogle ScholarPubMed
Toth, PP. Subclinical atherosclerosis: what it is, what it means and what we can do about it. Int J Clin Pract 2008;62:1246–5410.1111/j.1742-1241.2008.01804.xCrossRefGoogle Scholar
Li, F, Wang, X. Relationship between Framingham risk score and subclinical atherosclerosis in carotid plaques: an in vivo study using multi-contrast MRI. Sci China Life Sci 2017;60:23–710.1007/s11427-016-0385-5CrossRefGoogle Scholar
Jung, SY, Shim, HS, Hah, YM, Kim, SH, Yeo, SG. Association of metabolic syndrome with sudden sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg 2018;144:308–1410.1001/jamaoto.2017.3144CrossRefGoogle ScholarPubMed
Nagaoka, J, Anjos, MF, Takata, TT, Chaim, RM, Barros, F, Penido Nde, O. Idiopathic sudden sensorineural hearing loss: evolution in the presence of hypertension, diabetes mellitus and dyslipidemias. Braz J Otorhinolaryngol 2010;76:363–910.1590/S1808-86942010000300015CrossRefGoogle ScholarPubMed
Rudack, C, Langer, C, Stoll, W, Rust, S, Walter, M. Vascular risk factors in sudden hearing loss. Thromb Haemost 2006;95:454–61CrossRefGoogle ScholarPubMed
Mosnier, I, Stepanian, A, Baron, G, Bodenez, C, Robier, A, Meyer, B et al. Cardiovascular and thromboembolic risk factors in idiopathic sudden sensorineural hearing loss: a case-control study. Audiol Neurootol 2011;16:556610.1159/000312640CrossRefGoogle ScholarPubMed
Seo, YJ, Choi, JY, Moon, IS. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Dis Markers 2014;2014:70280710.1155/2014/702807CrossRefGoogle ScholarPubMed
Balta, S, Demırkol, S, Kucuk, U. The platelet lymphocyte ratio may be useful inflammatory indicator in clinical practice. Hemodial Int 2013;17:668–9Google ScholarPubMed
Chen, L, Zhang, G, Zhang, Z, Wang, Y, Hu, L, Wu, J. Neutrophil-to-lymphocyte ratio predicts diagnosis and prognosis of idiopathic sudden sensorineural hearing loss: a systematic review and meta-analysis. Medicine (Baltimore) 2018;97:e12492CrossRefGoogle ScholarPubMed
Kum, RO, Ozcan, M, Baklaci, D, Kum, NY, Yilmaz, YF, Unal, A et al. Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss. Braz J Otorhinolaryngol 2015;81:636–4110.1016/j.bjorl.2015.08.009CrossRefGoogle ScholarPubMed
Seaoud, E, Shawky, A. Framingham risk score and extent of atherosclerosis in non-diabetic patients with suspected coronary artery disease. J Ind Coll Cardiol 2018;8:182010.1016/j.jicc.2017.12.001CrossRefGoogle Scholar
Berrettini, S, Seccia, V, Fortunato, S, Forli, F, Bruschini, L, Piaggi, P et al. Analysis of the 3-dimensional fluid-attenuated inversion-recovery (3D-FLAIR) sequence in idiopathic sudden sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg 2013;139:456–6410.1001/jamaoto.2013.2659CrossRefGoogle ScholarPubMed
Weisel, JW. Fibrinogen and fibrin. Adv Protein Chem 2005;70:247–9910.1016/S0065-3233(05)70008-5CrossRefGoogle ScholarPubMed