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Idiopathic subglottic stenosis – a familial association and review of practice

Published online by Cambridge University Press:  29 April 2022

J M Hintze Open the ORCID record for J M Hintze [Opens in a new window] ,
C W Fitzgerald ,
I O'Riordan ,
E Keane ,
J Kinsella  and
C Timon
J M Hintze*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland Trinity College Dublin, University of Dublin, Dublin, Ireland Royal College of Surgeons in Ireland, Dublin, Ireland
C W Fitzgerald
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland Trinity College Dublin, University of Dublin, Dublin, Ireland Royal College of Surgeons in Ireland, Dublin, Ireland
I O'Riordan
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland Trinity College Dublin, University of Dublin, Dublin, Ireland Royal College of Surgeons in Ireland, Dublin, Ireland
E Keane
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland Trinity College Dublin, University of Dublin, Dublin, Ireland Royal College of Surgeons in Ireland, Dublin, Ireland
J Kinsella
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland Trinity College Dublin, University of Dublin, Dublin, Ireland
C Timon
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland Trinity College Dublin, University of Dublin, Dublin, Ireland
*
Author for correspondence: Dr Justin M Hintze, Department of Otolaryngology – Head and Neck Surgery, St James’ Hospital, Dublin, Ireland E-mail: hintzej@tcd.ie
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Abstract

Objective

Idiopathic subglottic stenosis describes subglottic stenosis where no inflammatory, traumatic, iatrogenic or other causative aetiology can be identified. The present study aimed to outline our institution's experience of patients diagnosed with idiopathic subglottic stenosis and describe a very rarely reported familial association.

Methods

A retrospective review was conducted of prospectively maintained medical records from 2011 to 2020. Patient clinical, radiological and intra-operative data were reviewed to assess for defined endpoints.

Results

Ten patients with idiopathic subglottic stenosis were identified in this series. One familial pairing was identified, with two sisters presenting with the condition. Successful treatment with carbon dioxide laser and dilatation was achieved in most cases.

Conclusion

Idiopathic subglottic stenosis represents a rare, clinically challenging pathology. Management with endoscopic laser and balloon dilatation is an effective treatment. This paper highlights a very rare familial association, and describes our experience in treating idiopathic subglottic stenosis.

Keywords

Tracheal StenosisAcquired Suglottic StenosisAirway ObstructionTracheaLaser Therapy
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 12 , December 2022 , pp. 1275 - 1277
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

*

Joint first authors

Dr J Hintze takes responsibility for the integrity of the content of the paper

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