Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-10T15:37:04.799Z Has data issue: false hasContentIssue false

Leiomyosarcoma of the larynx

Published online by Cambridge University Press:  29 June 2007

Julian M. Rowe-Jones*
Affiliation:
Departments of Otolaryngology – Head and Neck Surgery, Royal Surrey County and St Peter's Hospitals, Chertsey, Surrey.
Neil B. Solomons
Affiliation:
Departments of Otolaryngology – Head and Neck Surgery, Royal Surrey County and St Peter's Hospitals, Chertsey, Surrey.
Norman A. Ratcliffe
Affiliation:
Department of Histopathology, St Peter's Hospital, Chertsey, Surrey.
*
Julian M. Rowe-Jones, Department of Otolaryngology – Head and Neck Surgery, Charing Cross Hospital, Fulham Palace Road, London W6 8RF.

Abstract

Leiomyosarcoma of the larynx is extremely rare. Histological diagnosis excluding other tumours, in particular fibrosarcoma and spindle cell carcinoma is often difficult. Immunohistochemical studies are helpful in arriving at an unambiguous diagnosis and we present a case characteristically positive for actin and desmin. The difficulties of determining treatment are discussed.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chen, J. M., Norvick, W. H., Logan, C. A. (1991) Leiomyosarcoma of the larynx. Journal of Otolaryngology 20: 345348.Google ScholarPubMed
Cottran, R. S., Kumar, V., Robbins, S. L. (1989) The musculoskeletal system. In Robbins Pathologic Basis of Disease. 4th Edition.W. B. Saunders Co., Philadelphia, p 1377.Google Scholar
Eggston, A. A., Wolff, D. (1947) Histopathology of the Ear, Nose and Throat, Williams and Wilkins, Baltimore, p 959.Google Scholar
Frank, D. I. (1941) Leiomyosarcoma of the larynx. Archives of Otolaryngology 34: 493500.CrossRefGoogle Scholar
Freidmann, I., Piris, J. (1986) Neoplasms of the larynx. In Systematic Pathology, Vol. 1, Nose, Throat and Ears. 3rd Edition. (Friedmann, I., ed.), Churchill-Livingstone, London, p 240.Google Scholar
Fu, Y. S., Perzin, K. H. (1975) Nonepithelial tumours of the nasal cavity, paranasal sinuses, and nasopharynx: a clinicopathologic study. IV. Smooth muscle tumours (leiomyoma, leiomyosarcoma). Cancer 35: 13001308.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Haedicke, G., Kaban, L. B. (1988) Smooth-muscle tumours of the oral cavity. Plastic and Reconstructive Surgery 81: 264269.CrossRefGoogle ScholarPubMed
Kanabe, Y., Kondo, T., Hosada, S. (1969) Two cases of leiomyosarcoma of the maxillary sinus. Archives of Otolaryngology 90: 492495.Google Scholar
Kleinsasser, O., Glanz, H. (1979) Myogenic turnouts of the larynx. Archives of Otorhinolaryngology 225: 107119.CrossRefGoogle Scholar
Kuruvilla, A., Wenig, B. M., Humphrey, D. M.Heffner, D. K. (1990) Leiomyosarcoma of the sinonasal tract. A clinicopathologic study of nine cases. Archives of Otolaryngology, Head and Neck Surgery 116: 12781286.CrossRefGoogle ScholarPubMed
Michaels, L. (1987) Ear, Nose and Throat Histopathology. 1st Edition. Springer-Verlag, Berlin, pp 441443.CrossRefGoogle Scholar
Osborn, M., Domagala, W. (1991) Immunocytochemistry. In Comprehensive Cytopathology. 1st Edition. (Bibbo, M., ed.), W. B. Saunders Co., Philadelphia, pp 10111051.Google Scholar
Thedinger, B. A., Cheney, M. L., Montgomery, W. M., Goodman, M. (1991) Leiomyosarcoma of the trachea. Annals of Otology, Rhinology and Laryngology 100: 337340.CrossRefGoogle ScholarPubMed
Tighe, J. R., Davies, D. R. (1984) Pathology, 4th Edition. Bailliere-Tindall, London, p 73.Google Scholar
Wolfowitz, B. L., Schaman, A. (1973) Smooth-muscle tumours of the upper respiratory tract. South African Medical Journal 47: 11891191.Google ScholarPubMed