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Magnetic resonance imaging of Ménière's disease: early clinical experience in a UK centre

Published online by Cambridge University Press:  03 April 2020

I Pai ,
S Mendis ,
L Murdin ,
P Touska  and
S Connor
I Pai*
Affiliation:
Department of Otolaryngology, Guy's and St Thomas’ Hospital, London, UK
S Mendis
Affiliation:
Department of Otolaryngology, Guy's and St Thomas’ Hospital, London, UK
L Murdin
Affiliation:
Department of Otolaryngology, Guy's and St Thomas’ Hospital, London, UK
P Touska
Affiliation:
Department of Radiology, Guy's and St Thomas’ Hospital, London, UK
S Connor
Affiliation:
Department of Radiology, Guy's and St Thomas’ Hospital, London, UK School of Biomedical Engineering and Imaging Sciences Clinical Academic Group, King's College London, UK Department of Neuroradiology, Kings College Hospital, London, UK
*
Author for correspondence: Miss Irumee Pai, St Thomas’ Hearing Implant Centre, 2nd floor Lambeth Wing, St Thomas’ Hospital, Westminster Bridge Road, LondonSE1 7EH, UK E-mail: Irumee.Pai@gstt.nhs.uk Fax: +44 (0)20 7188 8905
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Abstract

Background

Recent developments in magnetic resonance imaging have enabled demonstration of endolymphatic hydrops, and the clinical application of these imaging studies in Ménière's disease is being explored.

Objective

To evaluate our centre's experience to date of hydrops magnetic resonance imaging in patients with episodic vertigo.

Methods

Magnetic resonance imaging was performed using a high-resolution three-dimensional fluid-attenuated inversion recovery sequence on a 3 Tesla scanner at 4 hours following double-dose gadolinium administration.

Results

The study included 31 patients, 28 of whom had a clinical diagnosis of Ménière's disease. In unilateral Ménière's disease, magnetic resonance imaging was able to lateralise endolymphatic hydrops to the clinically symptomatic ear in all cases. Mild hydrops was often seen in clinically asymptomatic ears.

Conclusion

There is a good correlation between the clinical symptoms and lateralisation of hydropic changes on magnetic resonance imaging. Further refinements of imaging techniques and grading system will likely improve the diagnostic accuracy and clinical utilisation of hydrops magnetic resonance imaging.

Keywords

Magnetic Resonance ImagingMeniere's DiseaseEndolymphatic HydropsVertigo
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 4 , April 2020 , pp. 302 - 310
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Miss I Pai takes responsibility for the integrity of the content of the paper

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