Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-28T23:51:58.406Z Has data issue: false hasContentIssue false

Management of intra-operative cerebrospinal fluid leak following endoscopic trans-sphenoidal pituitary surgery

Published online by Cambridge University Press:  25 November 2010

C G L Hobbs*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Western Health, Melbourne, Victoria, Australia
A Darr
Affiliation:
University of Keele School of Medicine, Stoke-on-Trent, UK
W V Carlin
Affiliation:
Department of Otolaryngology - Head and Neck Surgery, University Hospital of North Staffordshire, Stoke-on-Trent, UK
*
Address for correspondence: Mr Chris Hobbs, Department of Otolaryngology – Head and Neck Surgery, Western Hospital, Gordon Street, Footscray, Victoria, Australia3011 Fax: +61 3 8345 6735 E-mail: chris.hobbs@doctors.org.uk

Abstract

Objective:

Cerebrospinal fluid leakage is the most common complication of endoscopic trans-sphenoidal pituitary surgery. However, there is no uniformly accepted way of managing this complication when it occurs intra-operatively. This paper describes a quick, simple technique, involving layered fibrin glue and gelatin sponge, which does not compromise post-operative patient follow up.

Method:

Retrospective review of all endoscopic pituitary surgery cases conducted at a single institution since the introduction of this technique in 2002.

Results:

A total of 120 endoscopic pituitary operations were performed (96 primary procedures and 24 revisions). All intra-operative cerebrospinal fluid leaks were managed using the described method, with a failure rate of 3.6 per cent. The overall post-operative leakage rate was 1.7 per cent.

Conclusion:

This simple, conservative technique avoids the need for further dissection and the use of non-absorbable foreign material, and has a low incidence of post-operative cerebrospinal fluid leakage.

Type
Short Communications
Copyright
Copyright © JLO (1984) Limited 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Han, ZL, He, DS, Mao, ZG, Wang, HJ. Cerebrospinal fluid rhinorrhea following trans-sphenoidal pituitary macroadenoma surgery: experience from 592 patients. Clin Neurol Neurosurg 2008;110:570–9CrossRefGoogle ScholarPubMed
2van Aken, MO, de Marie, S, van der Lely, AJ, Singh, R, van den Berge, JH, Poublon, RM et al. Risk factors for meningitis after transsphenoidal surgery. Clin Infect Dis 1997;25:852–6CrossRefGoogle ScholarPubMed
3Tosun, F, Carrau, RL, Snyderman, CH, Kassam, A, Celin, S, Schaitkin, B. Endonasal endoscopic repair of cerebrospinal fluid leaks of the sphenoid sinus. Arch Otolaryngol Head Neck Surg 2003;129:576–80CrossRefGoogle ScholarPubMed
4Toma, AG, Fisher, EW, Cheesman, A. Autologous fibrin glue in the repair of dural defects in craniofacial resections. J Laryngol Otol 1992;106:356–7CrossRefGoogle ScholarPubMed
5Cappabianca, P, Cavallo, LM, Valente, V, Romano, I, D'Enza, AI, Esposito, F et al. Sellar repair with fibrin sealant and collagen fleece after endoscopic endonasal transsphenoidal surgery. Surg Neurol 2004;62:227–33CrossRefGoogle ScholarPubMed
6Kelly, DF, Oskouian, RJ, Fineman, I. Collagen sponge repair of small cerebrospinal fluid leaks obviates tissue grafts and cerebrospinal fluid diversion after pituitary surgery. Neurosurgery 2001;49:885–9Google ScholarPubMed
7Dusick, JR, Mattozo, CA, Esposito, F, Kelly, DF. BioGlue for prevention of postoperative cerebrospinal fluid leaks in transsphenoidal surgery: a case series. Surg Neurol 2006;66:371–6CrossRefGoogle ScholarPubMed