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Mast cell numbers in the mucosa of the inferior turbinate in patients with perennial allergic rhinitis: a light microscopic study

Published online by Cambridge University Press:  29 June 2007

A. B. Drake-Lee ,
B. Moriarty  and
Lesley A. Smallman
A. B. Drake-Lee*
Affiliation:
Birmingham
B. Moriarty
Affiliation:
Birmingham
Lesley A. Smallman
Affiliation:
Birmingham
*
Department of Otolaryngology, The Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH.
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Abstract

The number of mast cells in the inferior turbinate from patients with perennial allergy due to house dust mite were compared with ten normal controls. Ten random high powered fields were counted in the epithelium and the submucosa in samples which had been divided into two and fixed either in aqueous formaim or Carnoy's fixative. The sections from each block were stained with either Azure A or Chloroacetate esterase technique. No statistical differences were found. The lack of increase in mast cell numbers was attributed to degranulation since numbers have been shown to be increased in perennial allergy when sections are examined ultrastructurally.

Keywords

Mast cellsRhinitisallergicPathology
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 9 , September 1991 , pp. 736 - 738
Copyright
Copyright © JLO (1984) Limited 1991

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References

Cauna, N., Hindover, K., Manzethi, G., Swanson, E. (1972) Finestructure of nasal polyps. Annals of Otology, Rhinology and Laryngology, 81: 41–58.CrossRefGoogle Scholar
Drake-Lee, A. B., Chevretton, E., Lowe, D. (1988) The effects of different fixations on the distribution and numbers of mast cells in patients with nasal polyps. Journal of Laryngology and Otology, 102: 1099–1101.CrossRefGoogle ScholarPubMed
Drake-Lee, A. B., McLaughlin, P. (1982) Clinical symptoms, free histamine and IgE in nasal polyps. International Archives of Allergy and Applied Immunology, 69: 268–271.CrossRefGoogle Scholar
Drake-Lee, A. B., Price, J. (1990 a) A review of the morphology of human nasal mast cells studied by light and electron microscopy. Rhinology, in press.Google Scholar
Drake-Lee, A. B., Price, J. (1990 b) The ultrastructure of nasal mast cells in normal subjects and patients with parennial allergic rhinitis. Journal of Laryngology and Otology, 105: In Press.Google Scholar
Ehrlich, P. (1879) Beitrage zur kenntnis der granulitzen bindegewebs zellen und der eosinophilen leukocyten. Anatomie und Physiologie (Leipzig), 3: 166–169.Google Scholar
Enerback, L. (1981) The gut mucosal mast cells. Monographs of Allergy, 17: 222–232.Google Scholar
Enerback, L., Pipkom, U., Granurus, O. (1986) lntraepithelial mast cells in hay fever. International Archives of Allergy and Applied Immunology, 80: 44–51.CrossRefGoogle Scholar
Hardy, W., Westbrook, F. (1895) The wandering cells of the alimentary tract. Journal of Physiology, 18: 490–524.CrossRefGoogle Scholar
Hopwood, D. (1982) Fixation and fixatives. In: Theory and Practice of Histological Techniques. (Bancroft, J., Stevens, A., eds.) Churchill Livingstone: Ch. 2. 20–40.Google Scholar
Michels, N. (1938) the mast cells. In: Handbook of Haematology. (Downey, H., ed.) Hamish Hamilton Medical Books. London. 232–273.Google Scholar
Strobel, S., Miller, H., Ferguson, A. (1981) Human intestinal mast cells: Evaluation of fixation and staining techniques. Journal of Clinical Pathology, 34: 851–858.CrossRefGoogle ScholarPubMed
Trotter, C., Salter, D., Wilson, J., Hall, G. (1990) A comparison for nasal mast cell demonstration. Rhinology, 28: 17–23.Google ScholarPubMed
Viegas, M., Gomes, E., Brooks, J., Gatland, D., Davies, R. (1987) Effects of pollen season in nasal mast cells. British Medical Journal, 294: 414.CrossRefGoogle ScholarPubMed