Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-13T03:39:06.814Z Has data issue: false hasContentIssue false
  • English
  • Français

Metastasis of follicular variant of papillary thyroid carcinoma masquerading as primary temporal bone tumour

Published online by Cambridge University Press:  27 January 2011

S C Hugh ,
D Enepekides ,
J Wong ,
R Yeung  and
V Y W Lin
S C Hugh
Affiliation:
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
D Enepekides
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Wong
Affiliation:
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
R Yeung
Affiliation:
Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
V Y W Lin*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
*
Address for correspondence: Dr Vincent Lin, Dept of Otolaryngology – Head and Neck Surgery, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room M1-102, Toronto, Ontario, CanadaM4N 3M5 Fax: + 1 416 480 5761 E-mail: vincent.lin@sunnybrook.ca
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

We describe the first published case of papillary thyroid carcinoma metastatic to the temporal bone.

Case report:

A 64-year-old woman presented with a large left temporal bone mass centred in the jugular foramen, initially thought to be a paraganglioma or schwannoma. She was simultaneously being investigated for a left-sided thyroid nodule, which was found to be unremarkable on repeated fine needle aspiration cytology. A biopsy of the temporal bone mass indicated that it was of thyroid origin. The patient underwent total thyroidectomy, which enabled a final diagnosis of follicular-variant papillary thyroid carcinoma with metastasis to the temporal bone.

Conclusion:

Although biopsy is not the usual management for many types of temporal bone mass, pathological investigation is recommended if the tumour has an atypical growth rate, location, spread and/or radiological features. Metastasis of papillary thyroid carcinoma to the skull base is extremely rare, and correct diagnosis is essential in order to pursue an effective treatment plan.

Keywords

Thyroid NeoplasmCarcinomaNeoplasm MetastasisTemporal Bone
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 5 , May 2011 , pp. 528 - 532
Copyright
Copyright © JLO (1984) Limited 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Sherman, SI. Thyroid carcinoma. Lancet 2003;361:501–11CrossRefGoogle ScholarPubMed
2Yilmazlar, S, Kocaeli, H, Cordan, T. Sella turcica metastasis from follicular carcinoma of thyroid. Neurol Res 2004;26:74–8CrossRefGoogle ScholarPubMed
3Gilliland, FD, Hunt, WC, Morris, DM, Key, CR. Prognostic factors for thyroid carcinoma. A population-based study of 15,698 cases from the Surveillance, Epidemiology and End Results (SEER) program 1973–1991. Cancer 1997;79:564–733.0.CO;2-0>CrossRefGoogle Scholar
4Kachhara, R, Nair, S, Radhakrishnan, VV, Pandey, M, Ahmed, MI, Kumar, A et al. Solitary metastasis from occult follicular carcinoma of the thyroid mimicking trigeminal neurinoma – case report. Neurol Med Chir (Tokyo) 2001;41:360–3CrossRefGoogle ScholarPubMed
5Song, IS, Chan, KF, Tey, PH, Choi, HS. An unusual case of thyroid carcinoma metastasis to the posterior fossa. Mt Sinai J Med 1981;48:281–5Google Scholar
6Bell, CD, Kovacs, K, Horvath, E, Smythe, H, Asa, S. Papillary carcinoma of thyroid metastatic to the pituitary gland. Arch Pathol Lab Med 2001;125:935–8CrossRefGoogle ScholarPubMed
7Masiukiewicz, US, Nakchbandi, IA, Stewart, AF, Inzucchi, SE. Papillary thyroid carcinoma metastatic to the pituitary gland. Thyroid 1999;9:1023–7CrossRefGoogle ScholarPubMed
8Sziklas, JJ, Mathews, J, Spencer, RP, Rosenberg, RJ, Ergin, MT, Bower, BF. Thyroid carcinoma metastatic to pituitary. J Nucl Med 1985;26:1097Google ScholarPubMed
9Takami, T, Ohata, K, Tsuyuguchi, N, Mao, Y, Inoue, Y, Wakasa, K et al. Cavernous sinus metastasis from thyroid papillary adenocarcinoma. J Clin Neurosci 2002;9:598–600CrossRefGoogle ScholarPubMed
10Freeman, JL, Gershon, A, Liavaag, PG, Walfish, PG. Papillary thyroid carcinoma metastasizing to the sphenoid-ethmoid sinuses and skull base. Thyroid 1996;6:59–61CrossRefGoogle Scholar
11Baloch, ZW, LiVolsi, VA. Encapsulated follicular variant of papillary thyroid carcinoma with bone metastases. Mod Pathol 2000;13:861–5Google ScholarPubMed
12Nar Demirer, A, Ayturk, S, Tutuncu, NB, Gursoy, A, Pak, Y, Demirag, NG. Unresectable huge sternal and mediastinal metastasis of follicular thyroid carcinoma; radiotherapy as first-line and palliative therapy. Exp Clin Endocrinol Diabetes 2009;117:155–8Google ScholarPubMed
13Rosahl, SK, Erpenbeck, V, Vorkapic, P, Samii, M. Solitary follicular thyroid carcinoma of the skull base and its differentiation from ectopic adenoma – review, use of galectin-3 and report of a new case. Clin Neurol Neurosurg 2000;102:149–55CrossRefGoogle ScholarPubMed