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Metastatic cutaneous squamous cell carcinoma of the parotid gland: prognostic factors

Published online by Cambridge University Press:  05 July 2017

A C Coombs ,
A Butler  and
R Allison
A C Coombs*
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Dunedin Hospital, New Zealand
A Butler
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Christchurch Hospital, New Zealand
R Allison
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Christchurch Hospital, New Zealand
*
Address for correspondence: Dr Alice C Coombs, Department of Otolaryngology Head and Neck Surgery, Dunedin Hospital, 201 Great King Street, Dunedin 9016, New Zealand Fax: +64 (0)3 470 9959 E-mail: alice.coombs@southerndhb.govt.nz
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Abstract

Background:

Metastatic cutaneous squamous cell carcinoma is the most common parotid malignancy in Australasia. Prognostic indicators are not clearly defined and the extent of surgical resection required is controversial.

Methods:

A retrospective analysis was conducted of 63 patients who underwent surgery for metastatic cutaneous squamous cell carcinoma of the parotid gland at a tertiary hospital over a 10-year period.

Results:

The five-year overall survival rate was 53 per cent, the disease-specific survival rate was 78 per cent and the locoregional control rate was 72 per cent. Immunosuppression and no adjuvant radiotherapy were associated with a significant reduction in disease-specific survival. None of the factors analysed had a significant effect on locoregional control rates.

Conclusion:

More extensive surgery, including lateral temporal bone resection, may improve local control rates in cases of more advanced disease. The reduced survival of immunocompromised patients must be considered when planning their management.

Keywords

Skin NeoplasmsSquamous Cell CarcinomaMetastasisParotid GlandPrognosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 3 , March 2018 , pp. 264 - 269
Copyright
Copyright © JLO (1984) Limited 2017 

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Footnotes

Presented as a poster at the New Zealand Society of Otolaryngology, Head and Neck Surgery 69th Annual General and Scientific Meeting, 16–19 October 2016, Christchurch, New Zealand.

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