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Nasal polyposis in France: impact on sleep and quality of life

Published online by Cambridge University Press:  08 March 2006

Elie Serrano ,
Françoise Neukirch ,
Céline Pribil ,
Roger Jankowski ,
Jean-Michel Klossek ,
Isabelle Chanal  and
Abdelkader El Hasnaoui
Elie Serrano
Affiliation:
ENT Department, University Hospital of Toulouse, Hôpital Rangueil, Toulouse, INSERM 408, Paris, France
Françoise Neukirch
Affiliation:
ENT Department, University Hospital of Toulouse, Hôpital Rangueil, Toulouse, INSERM 408, Paris, France
Céline Pribil
Affiliation:
Laboratoire GlaxoSmithKline, Marly-le-Roi, France
Roger Jankowski
Affiliation:
ENT Department, University Hospital of Nancy, Hôpital Central, Nancy, France
Jean-Michel Klossek
Affiliation:
ENT Department University Hospital of Poitiers, Hôpital J Bernard, Poitiers, France
Isabelle Chanal
Affiliation:
Laboratoire GlaxoSmithKline, Marly-le-Roi, France
Abdelkader El Hasnaoui
Affiliation:
Laboratoire GlaxoSmithKline, Marly-le-Roi, France
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Abstract

The prevalence of nasal polyposis (NP) in France (2.11 per cent) and its epidemiology (detection, medical management, patients' characteristics, risk factors, associated diseases, etc.) were determined in a population-based, cross-sectional, case–control study of 10 033 adults carried out in 2002. The impact of this disease on daily living was also studied, by the analysis of potential sleep disorders (validated questionnaire) and quality of life (QOL, SF-36 questionnaire) of NP patients, in a comparison with a matched-control group of individuals without NP.

A quarter of NP patients (24.6 per cent) reported a feeling of general discomfort due to their nasal condition, during the day as well as the night in most of these cases (61.2 per cent). Compared with controls, NP patients have a two-fold higher risk of suffering sleep disturbance (odds ratio [OR]: 2.25, 95 per cent confidence interval [95% CI] [1.54; 3.29]). Snoring was reported by 50.5 per cent of NP patients vs 35.7 per cent of controls (p < 0.001). All scores from the SF-36 questionnaire demonstrated a significant negative impact of NP on the different aspects of QOL.

The current study underlines the negative impact of NP on QOL and sleep, two dimensions that are rarely considered in its pathology. In addition to the discomfort and lowered QOL experienced by patients with this disease, a significant increase in sleep disorders was shown, suggesting a risk of suffering further chronic diseases and complications.

Keywords

Nasal PolypsFranceEpidemiologyQuality Of LifeSleep
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 119 , Issue 7 , July 2005 , pp. 543 - 549
Copyright
© 2005 Royal Society of Medicine Press

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