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Nasal polyps in identical twins

Published online by Cambridge University Press:  29 June 2007

Adrian Drake-Lee*
Affiliation:
Birmingham
*
Adrian Drake-Lee, Ph.D., F.R.C.S. Consultant ENT Surgeon, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH

Abstract

Nasal polyps are multifactorial in aetiology but are associated with respiratory diseases, particularly late onset asthma. Several members of a family may be affected with nasal polyps but there is little evidence for a genetic basis for this. Some evidence to support a genetic predisposition comes from the development of polyps in identical twins.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1992

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References

Burger, J., Macek, M., Stuhrmann, M., Reis, A., Krawczak, M., Schmidtke, J. (1991) Genetic influences in the formation of nasal polyps. (Letters) Lancet, 1: 337974.Google Scholar
Cookson, W., Hopkin, J. (1988) Dominant inheritance of atopic immunoglobulin E responsiveness. Lancet, 1: 8688.Google Scholar
Cookson, W., Sharp, P., Faux, J., Hopkin, J. (1989) Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet, 1: 12921295.Google Scholar
Drake-Lee, A., Pitcher Willmott, R. (1982) The clinical and laboratory correlates of nasal polyps in cystic fibrosis. International Journal of Paediatric Otolaryngology, 4: 209214.Google Scholar
Drake-Lee, A., Lowe, D., Swanston, A., Grace, A. (1984) Clinical profile and recurrence of nasal polyps. Journal of Laryngology and Otology, 98: 783793.Google Scholar
Duffy, D., Martin, N., Battistutta, D., Hooper, J., Mathews, J. (1990) Genetics of asthma and hay fever in Australian twins. American Review of Respiratory Diseases, 142: 13511358.Google Scholar
Molony, J., Oliver, R. (1980) HLA antigens, nasal polyps and asthma. Clinical Otolaryngology, 5: 183189.Google Scholar
Pirson, F., Charpin, D., Sansonetti, M., Lanteaume, A., Kulling, G., Charpin, J., Vervloet, D. (1991) Is intrinsic asthma a hereditary disease? Allergy, 46: 367371.Google Scholar