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Nasopharyngeal amyloidosis: an unusual cause for epistaxis

Published online by Cambridge University Press:  16 June 2009

M A Oluk  and
J Murphy
M A Oluk*
Affiliation:
Department of Haematology, West Wales General Hospital, Carmarthen, Wales, UK
J Murphy
Affiliation:
Department of Haematology, West Wales General Hospital, Carmarthen, Wales, UK
*
Address for correspondence: Dr Margaret Atim Oluk, Flat 1, 4A Chalybeate Street, Aberystwyth, Wales SY23 1HS, UK. Fax: 01970 625 059 E-mail: Oluk2000@hotmail.co.uk
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Abstract

Objective:

We report the first case of nasal and nasopharyngeal amyloidosis secondary to multiple myeloma; this case also represents the fourth report of systemic nasal or nasopharyngeal amyloidosis.

Method:

Case report and review of the world literature concerning nasal and nasopharyngeal amyloidosis epidemiology, presentation and management.

Results:

Nasal and nasopharyngeal amyloidosis is rare. The presentation, clinical course and treatment are discussed for the presented patient. The amyloid tumour, which recurred in correlation with the progressive transformation of the multiple myeloma, was treated surgically. Subsequent localised radiotherapy decreased the size and growth rate of the tumour.

Conclusion:

Amyloid should be considered as a cause of resistant or recurrent epistaxis provided a mass lesion is seen on radiological imaging. Radiotherapy may be a treatment option in nasal and nasopharyngeal amyloidosis.

Keywords

Nasal CavityNasopharynxAmyloidMyeloma
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 2 , February 2010 , pp. 209 - 212
Copyright
Copyright © JLO (1984) Limited 2009

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