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Not just another paediatric neck lump: metastatic cribriform adenocarcinoma of the palate in an adolescent

Published online by Cambridge University Press:  19 February 2015

A S Takhar ,
A Simmons ,
L Ffolkes  and
N Hyde
A S Takhar*
Affiliation:
Department of ENT Surgery, St George's Hospital, London, UK
A Simmons
Affiliation:
Department of ENT Surgery, St George's Hospital, London, UK
L Ffolkes
Affiliation:
Department of Cellular Pathology, St George's Hospital, London, UK
N Hyde
Affiliation:
Department of Oral and Maxillofacial Surgery (Thomas Tatum Head and Neck Unit), St George's Hospital, London, UK
*
Address for correspondence: Mr A S Takhar, 46 Plato Road, Brixton, London SW2 5UR, UK E-mail: aruntakhar@doctors.org.uk
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Abstract

Objective:

This paper reports the case of a 13-year-old girl with a 2-year history of left cervical lymph node swelling that was diagnosed as metastatic cribriform adenocarcinoma of the tongue and minor salivary gland.

Case report:

A 13-year-old girl with a left, level II cervical lymph node underwent excisional biopsy after an ultrasound suggested suspicious features. The histology indicated polymorphous low-grade adenocarcinoma, and a primary lesion in the left palate was identified. The patient underwent left maxillectomy, neck dissection and reconstruction. Histological analysis of resection specimens led to a revised diagnosis of cribriform adenocarcinoma of the tongue and minor salivary gland.

Conclusion:

Cribriform adenocarcinoma of the tongue and minor salivary gland has recently been described as a separate entity to polymorphous low-grade adenocarcinoma in light of histological and behavioural differences, including higher rates of metastasis at presentation. This is the first report in the world literature of an adolescent with this entity. It is possible that some previous reports of polymorphous low-grade adenocarcinoma in childhood would have been more accurately described as cribriform adenocarcinoma of the tongue and minor salivary gland.

Keywords

Salivary GlandsPalateCarcinoma, CribriformAdenocarcinomaAdolescentHead And Neck Cancer
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 129 , Issue 2 , February 2015 , pp. 194 - 197
Copyright
Copyright © JLO (1984) Limited 2015 

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