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Nutritional support in patients with low volume chylous fistula following radical neck dissection

Published online by Cambridge University Press:  29 June 2007

M. Al-Khayat*
Affiliation:
The Departments of Otolaryngology, The Royal London Hospital, Whitechapel, London E1 1BB.
O. S. Kenyon
Affiliation:
The Departments of Otolaryngology, The Royal London Hospital, Whitechapel, London E1 1BB.
H. V. Fawcett
Affiliation:
The Departments of and Human Nutrition, The Royal London Hospital, Whitechapel, London E1 1BB.
J. Powell-Tuck
Affiliation:
The Departments of and Human Nutrition, The Royal London Hospital, Whitechapel, London E1 1BB.
*
Mr G. S. Kenyon, M.D., F.R.C.S., E.N.T. Department, Royal London Hospital Trust, Whitechapel, London E1 1BB.

Abstract

One of the well known complications of radical neck dissection is a chylous fistula, which results from injury to the thoracic duct as it enters the left subclavian vein. Such fistulae may cause considerable increased morbidity to a patient who is already debilitated by malignancy and by the increased catabolic response to surgery. Further surgery may be appropriate for those with a high fistula output but conservative therapy is normally advocated for the remainder. Nutritional and electrolyte support for these patients is essential and poses potential problems in management.

We present three such patients. One was fed parenterally and two enterally and in all cases the fistulae closed spontaneously. We examine the known physiological stimuli to chyle production and conclude that the enteral feedings of these patients with fat or an isomolar enteral feed does not, contrary to current belief, increase chyle flow or delay the healing of these fistulae.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1991

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References

Barrowman, J., Roberts, K. B. (1967). The role of the lymphatic system in the absorption of water from the intestine of the rat. Quarterly Journal of Experimental Physiology, 52: 1930.CrossRefGoogle Scholar
Benson, J., Lee, P. R., Scholer, J. F., Kim, K. S., Bollman, J. L. (1956). Water absorption from the intestine via portal and lymphatic pathways. American Journal of Physiology, 184: 441444.CrossRefGoogle ScholarPubMed
Borgstrom, B., Laurell, C. B. (1953). Studieson lymph and lymph-proteins during absorption of fat and saline by rats. Acta Physiologica Scandinavica, 29: 264280.CrossRefGoogle Scholar
Bozetti, F., Arullani, A., Baticci, F., Terno, G., Ammatuna, M., Capello, G. (1982). Management of lymphatic fistulas by total parenteral nutrition. Journal of Parenteral Nutrition, 6(6): 526527.CrossRefGoogle Scholar
Chang, R. W. S., Heley, J., Richardson, R., Egrail, S. (1988). Total parenteral nutrition: A four year audit. British Journal of Surgery, 73: 656658.CrossRefGoogle Scholar
Crumley, R. L., Smith, J. D. (1976). Postoperative chylous fistula. Prevention and management. Laryngoscope, 86: 804813.CrossRefGoogle ScholarPubMed
Guyton, A. C. (1987). Human Physiology and Mechanisms of Disease, 4th ed. Saunders, W. B.: London, p. 237245.Google Scholar
Hashim, S. A., Roholt, H. B., Babayan, V. K., van Itallie, T. B. (1964). Treatment of chyluria and chylothorax with medium chain triglycerides. New England Journal of Medicine, 270: 756761.CrossRefGoogle Scholar
Kinnaert, P. (1973). Anatomical variations in the cervical portion of the thoracic duct in man. Journal of Anatomy, 115 (1): 4552.Google ScholarPubMed
Metson, R., Alessi, D., Calcaterra, T. C. (1986). Tetracycline sclerotherapy for chylous fistula following neck dissection. Archives of Otolaryngology, 112: 651653.CrossRefGoogle ScholarPubMed
Read, N. W. (1984). Intestinal transport of fluids and electrolytes. In Textbook of Gastroenterology. (Bouchier, I. A. D., Allan, R. N., Hodgson, H. J. F., Keighley, M. R. B., eds). Balliere TyndalI: London., p. 409.Google Scholar
Simmonds, W. J. (1955). Some observations on the increase in thoracic duct lymph flow during intestinal absorption of fat in unanaesthetized rats. Australian Journal of Experimental Biology, 33: 305313.CrossRefGoogle ScholarPubMed
Spiro, J. D., Spiro, R. H., Strong, E. W. (1990). The management of chyle fistula. Laryngoscope, 100: 771774.CrossRefGoogle ScholarPubMed
Strong, E. W. (1969). Preoperative radiotherapy and radical neck dissection. Surgical Clinics of North America, 49: 271276.CrossRefGoogle ScholarPubMed
Stuart, W. J. (1907). Operative injuries of the thoracic duct in the neck. Edinburgh Medical Journal, 22: 301317.Google Scholar
Walls, E. W. (1981). The blood vascular and lymphatic systems. In Cunningham's Textbook of Anatomy. 12th ed. (Romanes, G. J., ed.), Oxford University Press: Oxford, p. 984.Google Scholar
Wright, D. A., Kenyon, G. S. (1987). Cancer of the neck. In Scott-Brown's Otolaryngology. 5th ed. Vol. 5 (Stell, P. M. and Kerr, A. G., eds.). Butterworths: London, p. 336337.Google Scholar
Younus, M., Chang, R. W. C. (1988). Chylefistula. Treatment with total parenteral nutrition. Journal of Laryngology and Otology 102: 384.CrossRefGoogle ScholarPubMed