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Per-operative antibiotic/steroid prophylaxis of tympanostomy tube otorrhoea: chemical or mechanical effect?

Published online by Cambridge University Press:  29 June 2007

C. A. Shinkwin ,
G. E. Murty ,
R. Simo  and
N. S. Jones
C. A. Shinkwin*
Affiliation:
Department of Otolaryngology, University Hospital, NottinghamLeicester, UK.
G. E. Murty
Affiliation:
Department of Otolaryngology, Leicester Royal Infirmary, Leicester, UK.
R. Simo
Affiliation:
Department of Otolaryngology, University Hospital, NottinghamLeicester, UK.
N. S. Jones
Affiliation:
Department of Otolaryngology, University Hospital, NottinghamLeicester, UK.
*
Address for correspondence: Mr C. A. Shinkwin, F.R.C.S., Department of Otolaryngology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH.
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Abstract

The per-operative instillation of ototopical antibiotic/steroid drops reduces the incidence of early otorrhoea after tympanostomy tube insertion. Whether this is due to the chemical properties of the antibiotic/steroid or simply the mechanical instillation of fluid is unclear. In this paired matched study of 161 subjects Gentisone HC was shown to significantly reduce the otorrhoea rate compared to normal saline (1.24 per cent compared with 9.32 per cent, p<0.005, difference 8.07 per cent, 95 per cent confidence interval for difference 3.21 per cent to 12.93 per cent). Capillary viscosimetry proved Gentisone HC to be more viscous than normal saline. The benefits are due to Gentisone HC's chemical properties, and Gentisone HC rather than normal saline instillation per-operatively is recommended when tympanostomy tubes are inserted.

Keywords

Otitis media with effusionMiddle ear ventilationGentamicinsSteroids
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 6 , June 1996 , pp. 531 - 533
Copyright
Copyright © JLO (1984) Limited 1996

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Footnotes

Presented to the Otorhinolaryngological Research Society, April 1994, Glasgow.

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