Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-26T18:55:29.669Z Has data issue: false hasContentIssue false

Platelet-rich plasma in otolaryngology

Published online by Cambridge University Press:  12 December 2016

M Stavrakas*
Affiliation:
Department of Otolaryngology – Head Neck Surgery, AHEPA University Hospital, Thessaloniki, Greece
P D Karkos
Affiliation:
Department of Otolaryngology – Head Neck Surgery, AHEPA University Hospital, Thessaloniki, Greece Agios Loukas Private Clinic, Thessaloniki, Greece
K Markou
Affiliation:
Department of Otolaryngology – Head Neck Surgery, AHEPA University Hospital, Thessaloniki, Greece
N Grigoriadis
Affiliation:
Genetics and IVF Unit, Department of Obstetrics and Gynecology, Medical School, Ioannina University, Thessaloniki, Greece Biogenea Pharmaceuticals Cord Blood Bank, Thessaloniki, Greece
*
Address for correspondence: Mr M Stavrakas, Department of Otolaryngology, AHEPA University Hospital, S. Kiriakidi 1, Thessaloniki 54621, Greece E-mail: mstavrakas@doctors.org.uk

Abstract

Background:

Platelet-rich plasma is a novel material that is being used more frequently in many surgical specialties.

Methods:

A literature review on the current and potential uses of platelet-rich plasma in otolaryngology was performed.

Results:

There is limited evidence on the use of platelet-rich plasma in otolaryngology compared with other specialties: only 11 studies on various subspecialties (otology, rhinology and laryngology) were included in the final review.

Conclusion:

Based on the limited number of studies, we cannot draw safe conclusions about the value of platelet-rich plasma in otolaryngology. Nevertheless, the available literature suggests that platelet-rich plasma holds promise for future research and may have a number of clinical applications.

Type
Review Articles
Copyright
Copyright © JLO (1984) Limited 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Gopalakrishnan, S, Venkatasamy, P, Vivekanandamurthy, K. A study on efficacy of autologous platelet rich plasma in myringoplasty. Online J Otolaryngol 2013;3:3651 Google Scholar
2 Sclafani, AP, Azzi, J. Platelet preparations for use in facial rejuvenation and wound healing: a critical review of current literature. Aesthetic Plast Surg 2015;39:495505 CrossRefGoogle ScholarPubMed
3 Pomerantz, J, Dutton, JM. Platelet gel for endoscopic sinus surgery. Ann Otol Rhinol Laryngol 2005;114:699704 CrossRefGoogle ScholarPubMed
4 Rice, DH. Platelet-rich plasma in endoscopic sinus surgery. Ear Nose Throat J 2006;85:516 CrossRefGoogle ScholarPubMed
5 Sidman, JD, Lander, TA, Finkelstein, M. Platelet-rich plasma for pediatric tonsillectomy patients. Laryngoscope 2008;118:1765–7CrossRefGoogle ScholarPubMed
6 Erkilet, E, Koyuncu, M, Atmaca, S, Yarim, M. Platelet-rich plasma improves healing of tympanic membrane perforations: experimental study. J Laryngol Otol 2009;123:482 CrossRefGoogle ScholarPubMed
7 Cho, HH, Jang, S, Lee, SC, Jeong, HS, Park, JS, Han, JY et al. Effect of neural-induced mesenchymal stem cells and platelet-rich plasma on facial nerve regeneration in an acute nerve injury model. Laryngoscope 2010;120:907–13CrossRefGoogle Scholar
8 Navarrete Álvaro, ML, Ortiz, N, Rodriguez, L, Boemo, R, Fuentes, J, Mateo, A et al. Pilot study on the efficiency of the biostimulation with autologous plasma rich in platelet growth factors in otorhinolaryngology: otologic surgery (tympanoplasty type I). ISRN Surg 2011:14 CrossRefGoogle Scholar
9 Salaheldin, AH, Hussein, A. Effect of platelet-rich plasma on nasal mucociliary clearance after submucous diathermy of inferior turbinate. EJENTAS 2012;13:71–5Google Scholar
10 Friji, M, Gopalakrishnan, S, Verma, S, Parida, P, Mohapatra, D. New regenerative approach to atrophic rhinitis using autologous lipoaspirate transfer and platelet-rich plasma in five patients: our experience. Clin Otolaryngol 2014;39:289–92CrossRefGoogle ScholarPubMed
11 Woo, SH, Jeong, H-S, Kim, JP, Koh, E-H, Lee, SU, Jin, SM et al. Favorable vocal fold wound healing induced by platelet-rich plasma injection. Clin Exp Otorhinolaryngol 2014;7:4752 CrossRefGoogle ScholarPubMed
12 Cobden, SB, Oztürk, K, Duman, S, Esen, H, Aktan, TM, Avunduk, MC et al. Treatment of acute vocal fold injury with platelet-rich plasma. J Voice 2015; doi: 10.1016/j.jvoice.2015.07.012 Google ScholarPubMed