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Prevalence of oesophagitis in patients with persistent upper respiratory symptoms

Published online by Cambridge University Press:  08 March 2006

F. Catalano ,
C. Terminella ,
C. Grillo ,
S. Biondi ,
M. Zappalà  and
C. Bentivegna
F. Catalano
Affiliation:
Gastroenterology and Digestive Endoscopy Service, University of Catania, Garibaldi Hospital, Catania, Italy.
C. Terminella
Affiliation:
Gastroenterology and Digestive Endoscopy Service, University of Catania, Garibaldi Hospital, Catania, Italy.
C. Grillo
Affiliation:
Otorhinolaryngology Unit, University of Catania, Italy.
S. Biondi
Affiliation:
Otorhinolaryngology Unit, University of Catania, Italy.
M. Zappalà
Affiliation:
Otorhinolaryngology Unit, University of Catania, Italy.
C. Bentivegna
Affiliation:
Gastroenterology and Digestive Endoscopy Service, University of Catania, Garibaldi Hospital, Catania, Italy.
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Abstract

A growing body of evidence suggests that a variety of upper respiratory symptoms (URS) are associated with gastro-oesophageal reflux (GORD). The aim of this study was to determine the prevalence of endoscopic erosive, and non-erosive, oesophagitis among patients complaining of persistent URS, in the absence of typical GORD symptoms, and to compare them with a comparison group of similar age. A group of 110 patients aged 18–75, presenting with persistent URS with no suspicion of GORD symptoms, underwent upper flexible endoscopy, with biopsy sampling for histology, and was compared with a group of 117 patients of similar age undergoing endoscopy for reasons other than GORD. Patients affected with upper airway disorders, such as posterior laryngitis, chronic sinusitis and vocal fold nodules, had a significantly higher prevalence of oesophagitis of varying degrees (31 per cent) compared to the comparison population(15.4 per cent) (p < 0.01). These data suggest that in many patients with chronic URS occult gastro-oesophageal diseases are present.

Keywords

Respiratory Tract InfectionsOesophagitisGastroesophageal Reflux
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 118 , Issue 11 , November 2004 , pp. 857 - 861
Copyright
© 2004 Royal Society of Medicine Press

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