Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-10T07:46:45.479Z Has data issue: false hasContentIssue false

Radiation-induced cranial nerve palsy: hypoglossal nerve and vocal cord palsies

Published online by Cambridge University Press:  29 June 2007

Toru Takimoto*
Affiliation:
Department of Otolaryngology, School of Medicine, Kanazawa University, Kanazawa, Japan.
Yasuo Saito
Affiliation:
Department of Radiology, School of Medicine, Kanazawa University, Kanazawa, Japan.
Masayuki Suzuki
Affiliation:
Department of Radiology, School of Medicine, Kanazawa University, Kanazawa, Japan.
Toshirou Nishimura
Affiliation:
Department of Otolaryngology, School of Medicine, Kanazawa University, Kanazawa, Japan.
*
Toru Takimoto, M.D., Department of Otolaryngology, School of Medicine, Kanazawa University, 13-1 Takaramachi, Kanazawa 920, Japan.

Abstract

Cranial nerve palsies are an unexpected complication of radiotherapy for head and neck tumours. We present a case of this radiation-induced cranial palsy.

An 18-year-old female with nasopharyngeal carcinoma developed a right hypoglossal nerve palsy 42 months after cancericidal doses of radiotherapy. In addition, she developed a bilateral vocal cord palsy 62 months after therapy. Follow-up over four years has demonstrated no evidence of tumour recurrence and no sign of neurological improvement.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ballantyne, A. J. (1975) Late sequelae of radiation therapy in cancer of the head and neck with particular reference to the nasopharynx. American Journal of Surgery, 130: 433436.CrossRefGoogle Scholar
Berger, P. S., Bataini, J. P. (1977) Radiation-induced cranial nerve palsy. Cancer, 40: 152155.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Cheng, V. S. T., Schulz, M. D. (1975) Unilateral hypoglossal nerve atrophy as a late complication of radiation therapy of head and neck carcinoma: A report of four cases and a review of the literature on peripheral and cranial nerve damages after radiation therapy. Cancer, 35: 15371544.3.0.CO;2-L>CrossRefGoogle Scholar
Janzen, A. H., Warren, S. (1942) Effect of Roentgen rays on the peripheral nerve of the rat. Radiology, 38: 333337.CrossRefGoogle Scholar
Johnston, E. F., Hammond, A. J., Cairncross, J. G. (1989) Bilateral hypoglossal palsies: A late complication of curative radiotherapy. Canadian Journal of Neurological Sciences, 16: 198199.CrossRefGoogle ScholarPubMed
Saunders, W. H., Hodgson, S. E. (1979) Bilateral hypoglossal nerve paralysis after irradiation therapy. Annals of Otology, Rhinology and Laryngotogy, 88: 515517, 1989.CrossRefGoogle ScholarPubMed
Mesic, J. B., Fletcher, G. H., Goepfert, H. (1981) Megavoltage irradiation of epithelial tumours of the nasopharynx. International Journal of Radiation, Oncology and Biological Physics, 7: 447453.CrossRefGoogle ScholarPubMed
Stoll, B. A., Andrew, J. T. (1966) Radiation induced peripheral neuropathy. British Medical Journal, 1: 834837.CrossRefGoogle ScholarPubMed