Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-26T18:14:16.337Z Has data issue: false hasContentIssue false
  • English
  • Français

Recurrent respiratory papillomatosis – the Manchester experience, 1974–1992

Published online by Cambridge University Press:  29 June 2007

C. Hartley ,
J. Hamilton ,
A. R. Birzgalis  and
W. T. Farrington
C. Hartley*
Affiliation:
Manchester Royal Infirmary and Christie Hospitals, Manchester.
J. Hamilton
Affiliation:
Manchester Royal Infirmary and Christie Hospitals, Manchester.
A. R. Birzgalis
Affiliation:
Manchester Royal Infirmary and Christie Hospitals, Manchester.
W. T. Farrington
Affiliation:
Manchester Royal Infirmary and Christie Hospitals, Manchester.
*
Mr C. Hartley, Department of Otolaryngology, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL
Get access Rights & Permissions [Opens in a new window]

Abstract

A series of 59 patients of all ages with recurrent respiratory papillomatosis (RRP) treated over an 18-year period is presented. A number of these patients were initially diagnosed in childhood but required treatment throughout adult life. The frequency of laser treatment was not related to either disease duration or age at onset. In 28 patients, the HPV type was identified, showing that HPV type 11 was more common in children and ran a more protracted clinical course. The requirement for tracheostomy in this series was small, whereas the incidence of malignant change in adult patients was significant

Keywords

PapillomaLaserLaryngeal diseases
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 3 , March 1994 , pp. 226 - 229
Copyright
Copyright © JLO (1984) Limited 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abramson, A. L., Steinberg, B. M., Winkler, B. (1987) Laryngeal papillomatosis: clinical, histopathologic and molecular studies. Laryngoscope 97: 678–685.CrossRefGoogle ScholarPubMed
Abramson, A. L., Waner, M., Brandsma, J. (1988) The clinical treatment of laryngeal papillomas with hematoporphyrin therapy. Archives of Otolaryngology, Head and Neck Surgery 114: 795–800.CrossRefGoogle ScholarPubMed
Aguado, D. L., Pinero, B. P., Betancor, L., Mendez, A., Banales, E. C. (1991) Acyclovir in the treatment of laryngeal papillomatosis. International Journal of Pediatric Otorhinolaryngology 21: 269–274.CrossRefGoogle Scholar
Bomholt, A. (1988) Juvenile laryngeal papillomatosis: an epidemiological study from the Copenhagen region. Acta Otolaryngologica (Stockholm) 105: 367–371.CrossRefGoogle ScholarPubMed
Capper, J. W. R., Bailey, C. M., Michaels, L. (1983) Squamous papilloma of the larynx in adults. Clinical Otolaryngology 8: 109–119.CrossRefGoogle ScholarPubMed
Chaput, M., Ninane, J., Gosseye, S., Moulin, D., Hamoir, M., Claus, D., Francis, C., Richard, F., Vermylen, C., Cornu, G. (1989) Juvenile laryngeal papillomatosis and epidermoid carcinoma. Journal of Pediatrics 114: 269–272.CrossRefGoogle ScholarPubMed
Clements, R., Gravelle, I. H. (1986) Laryngeal papillomatosis. Clinical Radiology 37: 547–550.CrossRefGoogle ScholarPubMed
Corbitt, G., Zarod, A. P., Arrand, J. R., Longson, M., Farrington, W. T. (1988) Human papilloma virus (HPV) genotypes associated with laryngeal papilloma. Journal of Clinical Pathology 41: 284–288.CrossRefGoogle ScholarPubMed
Irwin, B. C., Hendrickse, W. A., Pincott, J. R., Bailey, C. M., Evans, J. N. G. (1986) Juvenile laryngeal papillomatosis. Journal of Laryngology and Otology 100: 435–445.CrossRefGoogle ScholarPubMed
Jakubikova, J., Oravec, C., Klacansky, I. (1992) Modulation of humoral and cellular resistance in children with laryngeal papillomatosis. International Journal of Pediatric Otorhinolaryngology 23: 229–236.CrossRefGoogle ScholarPubMed
Leventhal, B. G., Kashima, H. K., Mounts, P., Thurmond, L., Chapman, S., Buckley, S., Wold, D. and the Papilloma Study Group (1991) Long-term response of recurrent respiratory papillomatosis to treatment with lymphoblastoid interferon alfa-nl. New England Journal of Medicine 325: 613–617.CrossRefGoogle Scholar
Lindeberg, H., Oster, S., Oxlund, I., Elbrond, O. (1986) Laryngeal papillomas: classification and clinical course. Clinical Otolaryngology 11: 423–429.CrossRefGoogle Scholar
Lindeberg, H., Syrjanen, S., Karja, J., Syrjanen, K. (1989) Human papilloma virus type 11 DNA in squamous cell carcinomas and pre-existing multiple laryngeal papillomas. Acta Otolaryngologica (Stockholm) 107: 141–149.CrossRefGoogle Scholar
MacKenzie, M. (1880) A Manual of Diseases of the Throat and Nose, Vol. 1, Diseases of the Pharynx, Larynx and Trachea, William Wood and Co., New York, p 305.Google Scholar
Mounts, P., Kashima, H. K. (1984) Association of human papilloma virus subtype and clinical course in respiratory papillomatosis. Laryngoscope 94: 28–33.CrossRefGoogle ScholarPubMed
Perrick, D., Wray, B. B., Leffell, M. S., Harmon, J. D., Porubsky, E. S. (1990) Evaluation of immunocompetency in juvenile laryngeal papillomatosis. Annals of Allergy 65: 69–72.Google ScholarPubMed
Quiney, R. E., Wells, M., Lewis, F. A., Terry, R. M., Michaels, L., Croft, C. B. (1989) Laryngeal papillomatosis: correlation between severity of disease and presence of HPV 6 and 11 detected by in situ DNA hybridisation. Journal of Clinical Pathology 42: 694–698.CrossRefGoogle ScholarPubMed
Schnadig, V. J., Clark, W. D., Clegg, T. J., Yao, C. S. (1986) Invasive papillomatosis and squamous carcinoma complicating juvenile laryngeal papillomatosis. Archives of Otolaryngology, Head and Neck Surgery 112: 966–971.CrossRefGoogle ScholarPubMed
Strong, M., Vaughan, C. W., Healy, B., Cooperband, S., Clemente, M. (1976) Recurrent respiratory papillomatosis. Annals of Otology, Rhinology and Laryngology 85: 508–516.CrossRefGoogle ScholarPubMed
Wetmore, S. J., Key, J. M., Suen, J. Y. (1985) Complications of laser surgery for laryngeal papillomatosis. Laryngoscope 95: 798–801.CrossRefGoogle ScholarPubMed