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Reversibility of mucociliary clearance and olfaction impairment following endoscopic sinus surgery: a prospective observational study

Published online by Cambridge University Press:  17 February 2021

V Hema ,
G Rebekah  and
R Kurien
V Hema
Affiliation:
Department of ENT, Christian Medical College, Vellore, India
G Rebekah
Affiliation:
Department of Biostatistics, Christian Medical College, Vellore, India
R Kurien*
Affiliation:
Department of ENT, Christian Medical College, Vellore, India
*
Author for correspondence: Dr Regi Kurien, Department of ENT, Christian Medical College, Vellore, Tamil Nadu, India – 632004 E-mail: regikurien@cmcvellore.ac.in Fax: +91 416 2232035
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Abstract

Objective

Chronic rhinosinusitis is associated with altered mucociliary clearance and olfaction. The study aimed to analyse the reversibility of impairment and endoscopic factors predicting changes in mucociliary clearance and olfactory parameters.

Methods

This prospective study included patients undergoing functional endoscopic sinus surgery for medically refractory chronic rhinosinusitis. Pre- and post-operative measurements of mucociliary clearance, olfactory thresholds, and identification scores were recorded.

Results

Of the 96 patients, 65.6 per cent had polyposis and 80.2 per cent underwent primary surgery. Improvements in mucociliary clearance and olfaction scores were seen in all patients, with greater reversibility of impairment in patients with polyposis and in those who underwent revision surgery. The presence of polyps correlated significantly with changes in mucociliary clearance and olfaction.

Conclusion

The study highlights improvements in mucociliary clearance, olfactory thresholds and identification scores after functional endoscopic sinus surgery in chronic rhinosinusitis with or without nasal polyposis, as well as for primary and revision surgeries. Adequate post-operative care and prevention of polyps recurrence help to improve mucociliary clearance and olfaction scores.

Keywords

Mucociliary ClearanceOlfactionSinusitis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 135 , Issue 2 , February 2021 , pp. 147 - 152
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr R Kurien takes responsibility for the integrity of the content of the paper

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