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The role of platelet-rich plasma in microlaryngeal surgery: a randomised, controlled trial

Published online by Cambridge University Press:  10 February 2022

A Gaafar Open the ORCID record for A Gaafar [Opens in a new window] ,
A Eldeghiedy ,
R ElMaghraby ,
I Nouh  and
M Donia
A Gaafar*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery Unit, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt
A Eldeghiedy
Affiliation:
Clinical Pathology, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt
R ElMaghraby
Affiliation:
Department of Otolaryngology, Phoniatrics Unit, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt
I Nouh
Affiliation:
Department of Otolaryngology, Head and Neck Surgery Unit, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt
M Donia
Affiliation:
Department of Otolaryngology, Head and Neck Surgery Unit, Alexandria Faculty of Medicine, Alexandria University, Alexandria, Egypt
*
Author for correspondence: Dr A Gaafar, Department of Otolaryngology, Head and Neck Surgery Unit, Faculty of Medicine, Alexandria University, Champollion Street, Alexandria21131, Egypt E-mail: alaa.gaafar@alexmed.edu.eg
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Abstract

Objective

Platelet-rich plasma has gained interest over the two last decades, mainly because of its role in regenerative medicine. This work aimed to assess the role of intra-operative local application of platelet-rich plasma gel in the improvement of quality of voice after microlaryngeal surgery.

Method

This was a prospective comparative study that included 40 patients undergoing microlaryngeal surgery for benign vocal fold lesions. There were two groups divided equally into study group A and control group B. The assessment of voice was performed by videostroboscopy and acoustic analysis pre-operatively and at two weeks and one and three months post-operatively.

Results

The data demonstrated that all the stroboscopic and acoustic parameters showed significant improvement in both groups. Group A showed significant improvement regarding acoustic parameters at the third post-operative follow up when compared with group B.

Conclusion

Platelet-rich plasma has a beneficial effect on voice quality following microlaryngeal surgery based in particular on acoustic parameters.

Keywords

Vocal CordsPlatelet-Rich PlasmaVoice Quality
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 8 , August 2022 , pp. 737 - 741
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Dr A Gaafar takes responsibility for the integrity of the content of the paper

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