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Salivary gland tumours as second neoplasms: two cases and literature review

Published online by Cambridge University Press:  19 November 2009

N Zidar ,
N Gale ,
A Župevc  and
M Žargi
N Zidar*
Affiliation:
Institute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
N Gale
Affiliation:
Institute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
A Župevc
Affiliation:
Department of Otorhinolaryngology and Cervicofacial Surgery, Clinical Center, Ljubljana, Slovenia
M Žargi
Affiliation:
Department of Otorhinolaryngology and Cervicofacial Surgery, Clinical Center, Ljubljana, Slovenia
*
Address for correspondence: Dr Nina Zidar, Institute of Pathology, Medical Faculty, Korytkova 2, 1000 Ljubljana, Slovenia. Fax: +386 1 543 71 01 E-mail: nina.zidar@mf.uni-lj.si
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Abstract

Objectives:

Patients who survive malignant tumours have an increased risk of second neoplasms, including those of the salivary glands. Mucoepidermoid carcinoma of the parotid gland is by far the most common type of second salivary gland tumour; other types have rarely been reported. We describe here two patients with a second tumour of the salivary glands.

Case reports:

The first patient was a 22-year-old woman with a low grade mucoepidermoid carcinoma of the parotid gland, which developed 21 years after completion of chemoradiotherapy for acute lymphoblastic leukaemia. The second patient was a 40-year-old woman with an epithelial-myoepithelial carcinoma of the buccal mucosa, which arose 11 years after treatment for two malignant neoplasms – retroperitoneal liposarcoma and squamous cell carcinoma of the uterine cervix.

Conclusions:

It is mandatory that survivors of cancer should be monitored carefully, so that the complications related to their previous disease and therapy are detected early and managed properly.

Keywords

Salivary Gland NeoplasmsMucoepidermoid CarcinomaTumour Metastasis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 5 , May 2010 , pp. 577 - 580
Copyright
Copyright © JLO (1984) Limited 2009

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