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Severe acute pancreatitis as a first symptom of primary hyperparathyroid adenoma: a case report

Published online by Cambridge University Press:  29 June 2007

Hironori Shimizu  and
Akira Kodama
Hironori Shimizu*
Affiliation:
Department of Otorhinolaryngology, Numazu City Hospital, Shizuoka, Japan.
Akira Kodama
Affiliation:
Department of Otorhinolaryngology, Numazu City Hospital, Shizuoka, Japan.
*
Address for correspondence: Dr Hironori Shimizu, M.D., Division of Developmental Genetics, Centre for Biochemical Science, Chiba University School of Medicine, Inohana 1-8-1, Chuo-Ku, Chiba 260, Japan. Fax: 81 43 226 2183
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Abstract

We present a case of severe acute pancreatitis in a 14-year-old boy that may have been caused by hyperparathyroidism. The clue to finding the parathyroid adenoma was the hypercalcaemia. Although the patient did have acute pancreatitis, no therapy had been effective until the discovery of the parathyroid adenoma. After the excision of the parathyroid adenoma, the function of the pancreas and serum calcium returned to normal. This result suggests a certain cause and effect relationship between hyperparathyroidism and acute pancreatitis.

Keywords

HyperporathyroidismAcute pancreatitisAdenomaparathyroid
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 6 , June 1996 , pp. 602 - 603
Copyright
Copyright © JLO (1984) Limited 1996

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References

Bess, M. A., Edis, A. J., vanHeerden, J. A. (1980) Hyperparathyroidism and pancreatitis, chance or a causal association? Journal of the American Medical Association 243: 246–247.CrossRefGoogle ScholarPubMed
Haverback, B. J., Dyce, B., Bundy, H., Edmondson, H. A. (1960) Trypsyn, trypsinogen and trypsin inhibitor in human pancreatic juice. American Journal of Medicine 29: 424–433.CrossRefGoogle Scholar
Ishida, T., Yokoe, T., Izumio, M. (1991) Nationwide survey of parathyroid operations in Japan (1980–1989). Endocrine Surgery 8: 37–45.Google Scholar
Ludwig, G. D., Chaykin, L. B. (1966) Pancreatitis associated with primary hyperparathyroidism. Medical Clinics of North America 50: 1403–1406.CrossRefGoogle Scholar
Mallette, L. E., Bilezikian, J. P., Heath, D. A., Aurbach, G. D. (1974) Primary hyperparathyroidism, clinical and biochemical features. Medicine 53: 127–133.CrossRefGoogle ScholarPubMed
Mixter, C. G., Keynes, M., Chir, M., Cope, O. (1962) Further experience with pancreatitis as a diagnostic clue to hyperparathyroidism. New England Journal of Medicine 266: 265–272.CrossRefGoogle Scholar
Nakane, Y. (1989) The New Encylopedia of Surgical Science Vol. 25. Nakayama Co., Tokyo, pp 251–268.Google Scholar
Palmer, M., Adami, H. O., Krusemo, U. B., Ljunghal, S. (1988) Increased risk of malignant disease after surgery for primary hyperparathyroidism. American Journal Epidemiology 127: 1033–1040.CrossRefGoogle ScholarPubMed
Paloyan, D., Simonowitz, D., Paloyan, E., Snyder, T. J. (1982) Pancreatitis associated with primary hyperparathyroidism. American Surgery 48: 366–368.Google ScholarPubMed
Russel, C. F., Edis, A. J. (1982) Surgery for primary hyperparathyroidism: experience with 500 consecutive cases and evaluation of the role or surgery in the asymptomatic patient. British Journal of Surgery 69: 244.CrossRefGoogle Scholar
Schmidt, H., Creutzfeldt, W. (1970) Calciphylactic pancreatitis and pancreatitis in hyperparathyroidism. Clinical Orthopedics and Related Research 69: 135–140.CrossRefGoogle ScholarPubMed
Sonoda, T., Takeuchi, M., Kinoshita, K., Kotake, T., Nagano, S., Itatani, H., Yachiku, S., Ookawa, T., Mizutani, S., Ikuma, F. (1972) Parathyroid tumor, as for primary hyperparathyroidism in Japan. Japanese Journal of Clinical Medicine 30: 247–251.Google ScholarPubMed