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Sinus computerized tomography in primary hypogammaglobulinaemia

Published online by Cambridge University Press:  29 June 2007

D. G. Snow ,
T. T. Hansel ,
P. E. Williams ,
A. B. Drake-Lee  and
R. A. Thompson
D. G. Snow*
Affiliation:
Department of Otolaryngology, Queen Elizabeth Hospital, Edgbaston, Birmingham B 15
T. T. Hansel
Affiliation:
Regional Department of Immunology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST
P. E. Williams
Affiliation:
Regional Department of Immunology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST
A. B. Drake-Lee
Affiliation:
Department of Otolaryngology, Queen Elizabeth Hospital, Edgbaston, Birmingham B 15
R. A. Thompson
Affiliation:
Regional Department of Immunology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST
*
Mr David Snow, F.R.C.S., ENT Department, Dudley Road Hospital, Dudley Road, Birmingham
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Abstract

Thirteen patients suffering from primary hypogammaglobulinaemia receiving intravenous immunoglobulin replacement therapy underwent computerized tomography of the paranasal sinuses. The CT scans were evaluated and related to clinical data from the patients, who were selected for study on the basis of having symptoms of rhinosinusitis. The scans varied from normal to demonstrating widespread sinus abnormality. Th.ere was no relationship between the scan findings and duration of ENT symptoms, range of current symptoms, or the interval between the onset of ENT symptoms and the start of intravenous immunoglobulin replacement therapy. It is nevertheless possible that prompt institution of replacement therapy, after correct diagnosis early in the course of the disease, may prevent the development of sinus disease refractory to such treatment.

Keywords

HypogammaglobulinaemiaTomographyX-ray computedParanasal sinuses
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 11 , November 1993 , pp. 1008 - 1010
Copyright
Copyright © JLO (1984) Limited 1993

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References

Calhoun, K. H., Waggenspack, G. A., Simpson, C. B., Hokanson, J. A., Bailey, B. J. (1991) CT evaluation of the paranasal sinuses in symptomatic and asymptomatic populations. Otolaryngology—Head and Neck Surgery 104: 480–483.Google Scholar
Hill, L. E. (1971) Clinical features of hypogammaglobulinaemia. In Hypogammaglobulinaemia in the United Kingdom. Report of the MRC working party on hvpogammaglohulinaemia. HMSO Special Report Series, No. 310 pp 9–34.Google Scholar
Karlsson, G., Petruson, B., Bjorkander, J., Hanson, L. A. (1985) Infection of the nose and paranasal sinuses in adult patients with immunodeficiency. Archives of Otolaryngology 111: 290–293.Google Scholar
Kennedy, D. W., Zinreich, S. J. (1988) The functional endoscopic approach to inflammatory sinus disease: current perspectives and technique modifications. American Journal of Rhinologv 2: 89–96.Google Scholar
Lund, V. J. (1987) Surgical management of sinusitis. In Scott-Brown's Otolaryngology. 5th Edition, vol. 4. (Mackay, I. S., Bull, T. R., eds.), Butterworths, London, pp 180–202.Google Scholar
Roifman, C. M., Lederman, H. M., Lavi, S., Stein, L. D., Levison, H., Gelfand, E. W. (1985) Benefit of intravenous IgG replacement in hypogammaglobulinaemic patients with chronic sinopulmonary disease. American Journal of Medicine 79: 171–174.CrossRefGoogle Scholar
Williams, P. E., White, A., Wilson, J. A., Yap, P. L. (1991) Penetration of administered IgG into the maxillary sinus and long-term clinical effects of intravenous immunoglobulin replacement therapy on sinusitis in primary hypogammaglobulinaemia. Acta Otolarvngologica (Stockholm) 110: 550–555.Google Scholar