Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-28T05:48:34.507Z Has data issue: false hasContentIssue false
  • English
  • Français

Squamous cell carcinomas of the head and neck: descriptive analysis of 1293 cases

Published online by Cambridge University Press:  29 June 2007

Sevgi Y. Kurtulmaz ,
Haldun Ş. Erkal ,
Meltem Serin ,
Atilla H. Elhan  and
Ahmet Çakmak
Sevgi Y. Kurtulmaz
Affiliation:
Department of Radiation Oncology, Ankara University Faculty of Medicine, Ankara, Turkey.
Haldun Ş. Erkal*
Affiliation:
Department of Radiation Oncology, Ankara University Faculty of Medicine, Ankara, Turkey.
Meltem Serin
Affiliation:
Department of Radiation Oncology, Ankara University Faculty of Medicine, Ankara, Turkey.
Atilla H. Elhan
Affiliation:
Department of Biostatistics, Ankara University Faculty of Medicine, Ankara, Turkey.
Ahmet Çakmak
Affiliation:
Department of Radiation Oncology, Ankara University Faculty of Medicine, Ankara, Turkey.
*
Address for correspondence: Haldun Şükrü Erkal, M.D., P.K. 40, Aşaǧi Ayranci, TR-06541, Ankara, Turkey. Fax: +90 312 363 45 45
Get access Rights & Permissions [Opens in a new window]

Abstract

Medical reports of 1293 patients with squamous cell carcinoma (SCC) of the head and neck were retrospectively evaluated. The patients were classified according to their age, sex, primary tumour localization and tumoral stage. There were 1181 males (91.3 per cent) and 112 females (8.7 per cent), with a male to female ratio of 10.5:1. The peak incidences for all primary tumour localizations were observed in the fifth decade. Most common primary tumour localizations were the larynx (71.1 per cent), the nasopharynx (10.1 per cent) and the oral cavity (8.8 per cent). Of all patients in whom staging was complete, 43.1 per cent presented at early and 56.9 per cent at advanced stages. The proportion of patients presenting with metastatic neck nodes was 34.4 per cent and the incidence of metastatic neck nodes increased with increasing T stage. The supraglottic region was the most common primary site among all laryngeal SCC, with a supraglottic to glottic SCC ratio of 1.5:1. Glottic SCC presented at earlier stages compared to supraglottic SCC. The incidence of nodal metastases increased with increasing T stage for SCC of the larynx, the oral cavity and the oropharynx.

Keywords

Head and neck neoplasmsCarcinoma, squamous cellNeoplasm stagingRadiotherapyEpidemiology
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 6 , June 1997 , pp. 531 - 535
Copyright
Copyright © JLO (1984) Limited 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ali, S., Tiwari, R., Snow, G. B., Waal, I. V. D. (1986) Incidence of squamous cell carcinoma of the head and neck: Report of 1,000 cases. Journal of Laryngology and Otology 100: 315–327.CrossRefGoogle ScholarPubMed
American Joint Committee on Cancer (1988) Manual for Staging of Cancer, 3rd Edition, (Beahrs, O. H., Henson, D. E., Hutter, R. V. P., Myers, M. H., eds.), J. B. Lippincott, Philadelphia.Google Scholar
Atkinson, L. (1975) Some features of the epidemiology of cancer of the larynx in Australia and Papua New Guinea. Laryngoscope 85: 1173–1184.CrossRefGoogle ScholarPubMed
Bocca, E., Pignataro, O., Oldini, C. (1983) Supraglottic laryngectomy: 30 years of experience. Annals of Otology, Rhinology and Laryngology 92: 14–18.CrossRefGoogle ScholarPubMed
Daly, C. J., Strong, E. W. (1975) Carcinoma of the glottic larynx. American Journal of Surgery 130: 489–492.CrossRefGoogle ScholarPubMed
Fayov, J. (1975) Carcinoma of the endolarynx: Results of irradiation. Cancer 35: 1525–1532.Google Scholar
Firat, D. (1982) Cancer Statistics in Turkey. Turkish Association for Cancer Research and Control, Ankara, Turkey.Google Scholar
Firat, D., Hayran, M. (1995) Cancer Statistics in Turkey and in the World (1990–1992). Turkish Association for Cancer Research and Control, Ankara, Turkey.Google Scholar
Fleiss, J. L. (1981) Statistical Methods for Rates and Proportions, 2nd Edition, Wiley, New York, N.Y., pp. 138–143.Google Scholar
Hawkins, N. V. (1975) The treatment of glottic carcinoma: An analysis of 800 cases. Laryngoscope 85: 1485–1493.CrossRefGoogle ScholarPubMed
Iwamoto, H. (1975) An epidemiological study of laryngeal cancer in Japan (1960–1969). Laryngoscope 85: 1162–1172.CrossRefGoogle Scholar
Jankovic, I., Merkas, Z. (1976) Radiotherapy as the primary approach in the treatment of laryngeal cancer. In: Workshops from the Centennial Conference on Laryngeal Cancer (Alberti, P. W., Bryce, D. P., eds.), Appleton Century Crofts, East Norwalk, CT, p. 881.Google Scholar
Lauerma, S. (1967) Treatment of laryngeal cancer: A study of 638 cases. Ada Otolaryngologica (Suppl) 225: 1.Google Scholar
Lindberg, R. (1972) Distribution of cervical lymph node metastases from squamous cell carcinoma of the upper respiratory digestive tracts. Cancer 29: 1446–1449.3.0.CO;2-C>CrossRefGoogle Scholar
Mesic, J. B., Fletcher, G. H., Goepfert, H. (1981) Megavoltage irradiation of epithelial tumours of the nasopharynx. International Journal of Radiation Oncology, Biology, Physics 7: 447–453.CrossRefGoogle ScholarPubMed
Shah, J. P., Tollefsen, H. R. (1974) pidermoid carcinoma of the supraglottic larynx: Role of neck dissection in initial surgical treatment. American Journal of Surgery 128: 494–499.CrossRefGoogle Scholar
Siegel, S. (1956) Nonparametric Statistics for the Biomedical Sciences McGraw-Hill, New York, N.Y., pp. 213–229.Google Scholar
Smith, R. R., Caulk, R., Frazell, E., Holinger, P., Maccomb, W. S., Russell, W. O., Schulz, M. D., Tucker, G. F. (1973) Revision of the clinical staging system for cancer of the larynx. Cancer 31: 72–80.3.0.CO;2-V>CrossRefGoogle ScholarPubMed
Spitz, M. R. (1994) Epidemiology and risk factors for head and neck cancer. Seminars in Oncology 21: 281–288.Google ScholarPubMed
Till, J. E., Bruce, W. R., Elwan, A., Till, M. J., Niederer, J., Reid, J., Hawkins, N. V., Rider, W. D. (1975) A preliminary analysis of end results for cancer of the larynx. Laryngoscope 85: 259–275.CrossRefGoogle ScholarPubMed
Tuyns, A. J., Estevr, J., Riboli, E. (1984) Laryngeal and pharyngeal cancer in South-Western Europe. In IARC Annual Report. International Agency for Research on Cancer, Lyon.Google Scholar