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Submucosal neoplasms of the laryngeal introitus

Published online by Cambridge University Press:  25 May 2012

A D Friedman ,
J A Burns ,
M J Lutch  and
S M Zeitels
A D Friedman*
Affiliation:
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
J A Burns
Affiliation:
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
M J Lutch
Affiliation:
Department of Otolaryngology, Southern California Permanente Medical Group, San Diego, California, USA
S M Zeitels
Affiliation:
Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
*
Address for correspondence: Dr Aaron D Friedman, Massachusetts General Hospital, Center for Laryngeal Surgery and Voice Rehabilitation, One Bowdoin Square, 11th Floor, Boston, MA 02114, USA Fax: +1 617 726 0222 E-mail: afriedman3@partners.org
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Abstract

Background:

The differential diagnosis of endolaryngeal mesenchymal neoplasms includes a wide spectrum of benign and malignant pathologies, which have been rarely photo-documented and assessed as a group.

Methods:

Non-epithelial neoplasms of the endolarynx seen at our centre from 2002 to 2011 (n = 38; 36 treated at our institution) were retrospectively reviewed, with attention to clinical presentation, radiographic imaging, operative management, histology, and pre- and post-operative endoscopy. Submucosal squamous cell carcinomas, mucosal cysts, amyloid and Teflon granulomas were excluded.

Results:

Twenty-three of a total of 36 patients underwent definitive endoscopic surgical treatment. Supraglottic pathologies included lymphoma, lipoma, neuroendocrine carcinoma, lymphangioma, oncocytoma, haemangioma, synovial cell sarcoma and benign spindle cell neoplasm. Transglottic pathologies included synovial cell sarcoma and granular cell tumour. Glottic pathologies included granular cell tumour, osteoma, rhabdomyoma, rhabdomycosarcoma and myofibroblastic sarcoma. Subglottic pathologies included chondrosarcoma, neurofibroma, adenoid cystic carcinoma and vascular malformation.

Conclusion:

The site of origin, degree of malignant behaviour and sensitivity to adjuvant treatment determined the course of surgical management, i.e. endolaryngeal versus transcervical, and limited removal versus wider resection.

Keywords

LarynxLaryngeal NeoplasmsLaryngeal CancerSarcoma, SynovialChondrosarcomaGranular Cell Tumor
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 7 , July 2012 , pp. 706 - 713
Copyright
Copyright © JLO (1984) Limited 2012

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Footnotes

Presented as a poster at the Eastern Section Meeting of the Triological Society, 23–25 January 2009, Boston, Massachusetts, USA

References

1Thompson, LD, Gannon, FH. Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol 2002;26:836–51CrossRefGoogle ScholarPubMed
2Zeitels, SM, Jarboe, J, Franco, RA. Phonosurgical reconstruction of early glottic cancer. Laryngoscope 2001;111:1862–5CrossRefGoogle ScholarPubMed
3Zeitels, SM. Optimizing voice after endoscopic partial laryngectomy. Otolaryngol Clin North Am 2004;37:627–36CrossRefGoogle ScholarPubMed
4Sataloff, RT, Ressue, JC, Portell, M, Harris, RM, Ossoff, R, Merati, AL et al. Granular cell tumors of the larynx. J Voice 2000;14:119–34CrossRefGoogle ScholarPubMed
5De Vincentiis, M, Greco, A, Mascelli, A, Soldo, P, Zambetti, G. Lipoma of the larynx: a case report. Acta Otorhinolaryngol Ital 2010;30:58–63Google ScholarPubMed
6Ebmeyer, J, Reineke, U, Gehl, HB, Hamberger, U, Mlynski, R, Essing, M et al. Schwannoma of the larynx. Head Neck Oncol 2009;1:24CrossRefGoogle ScholarPubMed
7Lomeo, P, McDonald, J, Finneman, J. Adult laryngeal hemangioma: report of four cases. Ear Nose Throat J 2000;79:594, 597–8CrossRefGoogle ScholarPubMed
8Zeitels, SM, Burns, JA, Lopez-Guerra, G, Anderson, RR, Hillman, RE. Photoangiolytic laser treatment of early glottic cancer: a new management strategy. Ann Otol Rhinol Laryngol Suppl 2008;199:3–24CrossRefGoogle Scholar
9Franco, RA Jr, Zeitels, SM, Farinelli, WA, Anderson, RR. 585-nm pulsed dye laser treatment of glottal papillomatosis. Ann Otol Rhinol Laryngol 2002;111:486–92CrossRefGoogle ScholarPubMed
10Zeitels, SM, Akst, LM, Bums, JA, Hillman, RE, Broadhurst, MS, Anderson, RR. Pulsed angiolytic laser treatment of ectasias and varices in singers. Ann Otol Rhinol Laryngol 2006;115:571–80CrossRefGoogle ScholarPubMed
11Zeitels, SM, Burns, JA, Akst, LM, Hillman, RE, Broadhurst, MS, Anderson, RR. Office-based and microlaryngeal applications of a fiber-based thulium laser. Ann Otol Rhinol Laryngol 2006;115:891–6CrossRefGoogle ScholarPubMed
12Kishimoto, Y, Hirano, S, Kato, N, Suehiro, A, Kanemaru, S, Ito, J. Endoscopic KTP laser photocoagulation therapy for pharyngolaryngeal venous malformations in adults. Ann Otol Rhinol Laryngol 2008;117:881–5CrossRefGoogle ScholarPubMed
13Cai, X, Wang, T, Shi, L. Nonepithelial malignant neoplasms of the larynx and hypopharynx [in Chinese]. Zhonghua Er Bi Yan Hou Ke Za Zhi 1998;33:113–6Google ScholarPubMed
14Fernandez-Acenero, MJ, Larach, F, Ortega-Fernandez, C. Non-epithelial lesions of the larynx: review of the 10-year experience in a tertiary Spanish hospital. Acta Otolaryngol 2009;129:108–12CrossRefGoogle Scholar
15Bilgic, B, Mete, O, Ozturk, SA, Demiryont, M, Keles, N, Basaran, M. Synovial sarcoma: a rare tumor of larynx. Pathol Oncol Res 2003;9:242–5CrossRefGoogle ScholarPubMed
16Harb, WJ, Luna, MA, Patel, SR, Ballo, MT, Roberts, DB, Sturgis, EM. Survival in patients with synovial sarcoma of the head and neck: association with tumor location, size, and extension. Head Neck 2007;29:731–40CrossRefGoogle ScholarPubMed
17Quinn, HJ Jr.Synovial sarcoma of the larynx treated by partial laryngectomy. Laryngoscope 1984;94:1158–61CrossRefGoogle ScholarPubMed
18Lee, N, Shin, E. Treatment outcomes for patients with synovial sarcoma of the head and neck. Expert Rev Anticancer Ther 2008;8:371–3CrossRefGoogle ScholarPubMed