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Therapeutic indications for sinonasal topical steroid treatment and its effects on eosinophilic chronic rhinosinusitis after endoscopic sinus surgery

Published online by Cambridge University Press:  23 August 2021

T Saito ,
K Okazaki ,
Y Hamada ,
K Hashimoto  and
K Tsuzuki
T Saito*
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
K Okazaki
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
Y Hamada
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
K Hashimoto
Affiliation:
Department of Otorhinolaryngology, Hospital of Kawanishi City, Kawanishi, Japan
K Tsuzuki
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
*
Author for correspondence: Dr T Saito, Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, 1-1 Mukogawa, Nishinomiya, Hyogo663-8501, Japan E-mail: t-saito@hyo-med.ac.jp Fax: +81 798 41 8976
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Abstract

Objective

This study evaluated the post-operative indications for sinonasal topical steroid treatment using a corticosteroid (steroid)-eluting, sinus-bioabsorbable device and its effects in patients with eosinophilic chronic rhinosinusitis.

Method

Post-operative courses were investigated in two groups: group A with patients who underwent sinonasal topical steroid treatment, and group B with control patients who did not.

Results

Group A was significantly younger than group B (p < 0.01), and the pre-operative computed tomography score was significantly higher in group A than in group B (p < 0.05). In the post-operative stage, the nasal symptoms questionnaire component of olfactory loss and the post-operative endoscopic appearance score were significantly worse in group A than in group B (p < 0.01).

Conclusion

These data suggest that younger age, more severe rhinosinusitis and post-operative olfactory loss led to the need for sinonasal topical steroid treatment to prevent relapsing inflammation after functional endoscopic sinus surgery in patients with eosinophilic chronic rhinosinusitis.

Keywords

Paranasal SinusesEndoscopyNasal Surgical ProceduresPostoperative PeriodRecurrence
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 135 , Issue 10 , October 2021 , pp. 858 - 863
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr T Saito takes responsibility for the integrity of the content of the paper

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