Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-27T14:02:55.242Z Has data issue: false hasContentIssue false
  • English
  • Français

Ultrasound-guided core needle biopsy of parotid gland swellings

Published online by Cambridge University Press:  30 September 2008

R Pratap ,
A Qayyum ,
N Ahmed ,
P Jani  and
L H Berman
R Pratap
Affiliation:
Department of Otolaryngology, Norfolk and Norwich University Hospital, Norwich, UK
A Qayyum*
Affiliation:
Department of Otolaryngology, Norfolk and Norwich University Hospital, Norwich, UK Ipswich Hospital, Ipswich, UK
N Ahmed
Affiliation:
Addenbrookes University Hospital, Cambridge, UK
P Jani
Affiliation:
Addenbrookes University Hospital, Cambridge, UK
L H Berman
Affiliation:
Addenbrookes University Hospital, Cambridge, UK
*
Address for correspondence: Mr Asad Qayyum, 16 Lavendon House, 8 Paveley Street, London NW8 8TJ, UK. E-mail: asadqayyum@doctors.net.uk
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To determine whether ultrasound-guided core needle biopsy is a safe and reliable investigation in cases of parotid swelling in which fine needle aspiration cytology has failed to give a definitive diagnosis.

Design:

Analysis of 66 ultrasound-guided core biopsy specimens of the parotid gland (the largest series reported thus far) sample number refers to histological samples throughout the paper.

Subjects:

All the 184 cases of parotid surgery with a histological diagnosis were included.

Main outcome measures:

The sensitivity, positive predictive value and diagnostic accuracy of fine needle aspiration cytology and ultrasound-guided core needle biopsy, as compared with the final histological analysis.

Results:

Of a total of 184 patients, 89.1 per cent (164/184) had benign parotid lesions excised. The sensitivity, positive predictive value and diagnostic accuracy of fine needle aspiration cytology for benign lesions were 76.2, 84.2 and 87.5 per cent, respectively, and those of ultrasound-guided core needle biopsy were 91.7, 98.2 and 96.4 per cent, respectively. Twenty of 184 patients (10.9 per cent) had malignant lesions. The sensitivity, positive predictive value and diagnostic accuracy of fine needle aspiration cytology for detection of malignant lesions were 60, 75 and 75 per cent, respectively, while those of ultrasound-guided core biopsy were 89, 100 and 100 per cent, respectively. Non-diagnostic rates were 25.8 per cent for fine needle aspiration cytology and 4.5 per cent for ultrasound-guided core biopsy. Only one case of complications (a sub-clinical haematoma) occurred in the ultrasound-guided core biopsy group.

Conclusion:

We propose ultrasound-guided core needle biopsy as a very safe and effective tool in cases of parotid swelling in which fine needle aspiration cytology has failed to give a definitive diagnosis.

Keywords

Parotid NeoplasmsNeedle BiopsyDiagnosis
Type
Short Communications
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 4 , April 2009 , pp. 449 - 452
Copyright
Copyright © JLO (1984) Limited 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Layfield, LJ, Tan, P, Glasgow, BJ. Fine needle aspiration of salivary gland lesions. Arch Pathol Lab Med 1987;111:346–53Google ScholarPubMed
2 Brachtel, EF, Pilch, BZ, Khettry, U, Zembivicz, A, Faquin, WC. Fine needle aspiration biopsy of a cystic pleomorphic adenoma with extensive adnexa-like differentiation: differential diagnostic pitfall with mucoepidermoid carcinoma. Diagn Cytopathol 2003;28:100–3CrossRefGoogle ScholarPubMed
3 Parwani, AV, Ali-Sayed, Z. Diagnostic accuracy and pitfalls in the fine needle interpretation of Warthin's tumour. Cancer 2003;99:166–71CrossRefGoogle Scholar
4 Loggins, JP, Urquhart, A. Pre-operative distinction of parotid lymphomas. J Am Coll Surg 2004;199:58–61Google Scholar
5 Cohen, EG, Patel, SG, Lin, O, Boyle, JO, Kraus, DH, Singh, B et al. Fine needle aspiration biopsy of salivary gland lesion in a selected patient population. Arch Otolaryngol Head Neck Surg 2004;130:773–8CrossRefGoogle Scholar
6 Wan, YL, Chan, SC, Chen, YL, Cheung, YC, Lui, KW, Wong, HF et al. Ultrasonography-guided core-needle biopsy of parotid gland masses. Am J Neuroradiol 2004;25:1608–12Google ScholarPubMed
7 Buckland, JR, Manjaly, G, Violaris, N, Howlett, DC. Ultrasound-guided cutting-needle biopsy of the parotid gland. J Laryngol Otol 1999;113:988–92CrossRefGoogle ScholarPubMed
8 Kesse, KW, Manjaly, G, Violaris, N, Howlett, DC. Ultrasound-guided biopsy in the evaluation of focal and diffuse swelling of the parotid gland. Br J Oral Maxillofac Surg 2002;40:384–8CrossRefGoogle ScholarPubMed
9 Ellis, GL, Auclair, PL. Fine Needle Aspiration Biopsy of Salivary Glands. Tumours of Salivary Glands. Washington DC: Armed Forces Institute of Pathology, 1995;441Google Scholar
10 Roland, NJ, Caslin, AW, Smith, PA, Turnbull, LS, Panarese, A, Jones, AS. Fine needle aspiration cytology of salivary gland lesions reported immediately in a head and neck clinic. J Laryngol Otol 1993;107:1025–8CrossRefGoogle Scholar
11 Sadler, GP, McGee, S, Dallimore, NS, Monypenny, IJ, Douglas-Jones, AG, Lyons, K et al. Role of fine-needle aspiration cytology and needle-core biopsy in the diagnosis of carcinoma of the breast. Br J Surg 1994;81:1315–17CrossRefGoogle ScholarPubMed
12 Bearcroft, PWP, Berman, LH, Grant, J. The use of ultrasound-guided cutting-needle biopsy in the neck. Clin Radiol 1995;50:690–5CrossRefGoogle ScholarPubMed
13 Ochi, K, Ohashi, T, Ogino, S. Biopsy of head and neck lesions with a Biopty biopsy instrument [in Japanese]. Nippon Jibiinkoka Gakkai Kaiho 1992;95:551–5CrossRefGoogle ScholarPubMed
14 McGuirt, WF, McCabe, BF. Significance of node biopsy before definitive treatment of cervical metastatic carcinoma. Laryngoscope 1978;88:594–7CrossRefGoogle ScholarPubMed
15 Roussel, F, Dalion, J, Benozio, M. The risk of tumour seeding in needle biopsies. Acta Cytol 1989;33:936–9Google ScholarPubMed
16 Yamaguchi, KT, Strong, MS, Shapsay, SM, Soto, E. Seeding of parotid carcinoma along Vim-Silverman needle tract. J Otolaryngol 1979;8:49–52Google ScholarPubMed
17 Peacock, EE, Byars, LT. Management of tumours of the parotid gland. N C Med J 1958;19:1–9Google Scholar
18 Henriksson, G, Westrin, KM, Carlsoo, B, Silfversward, C. Recurrent primary pleomorphic adenomas of salivary gland origin: intrasurgical rupture, histopathologic features, and pseudopodia. Cancer 1998;82:617–203.0.CO;2-I>CrossRefGoogle ScholarPubMed