Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-13T08:55:25.883Z Has data issue: false hasContentIssue false

The value of the twinkling artefact for the diagnosis of sialolithiasis of the large salivary glands

Published online by Cambridge University Press:  18 December 2017

G Pabst*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Cantonal Hospital, Lucerne, Switzerland
K Strobel
Affiliation:
Department of Radiology and Nuclear Medicine, Cantonal Hospital, Lucerne, Switzerland
J Zehnder
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Cantonal Hospital, Lucerne, Switzerland
*
Address for correspondence: Dr Gunther Pabst, Department of Otolaryngology – Head and Neck Surgery, Luzerner Kantonsspital, Spitalstrasse 1, 6000 Luzern 16, Switzerland Fax: +41 41 205 2151 E-mail: gunther.pabst@luks.ch

Abstract

Objective:

The imaging of stones in the salivary glands and ducts poses a challenge, even to experienced ultrasound examiners. This study investigated whether the ‘twinkling artefact’, which occurs at internal calcific foci during Doppler ultrasound examinations, is useful for detecting salivary gland stones.

Methods:

In a model test, 20 salivary stones were analysed in vitro, via Doppler ultrasound, with regard to their representability and the triggering of the twinkling artefact. In a follow-up study, 28 patients with sialolithiasis and food-related large salivary gland swellings were examined, using both power and colour Doppler modes, with regard to the twinkling artefact. All ultrasound examinations were performed by an experienced examiner and retrospectively graded by two experienced sonographers.

Results:

All stones could reliably be detected using the twinkling artefact in the model test. Twenty-seven of 28 salivary stones (96 per cent) also showed twinkling in vivo, during patient assessment. The power Doppler mode showed a significantly higher intensity level of twinkling than the colour Doppler mode (p < 0.0001).

Conclusion:

The twinkling artefact is a very reliable sign for the diagnosis of sialolithiasis. Power Doppler is superior to colour Doppler for detection of the twinkling artefact.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 2017 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Rauch, S, Gorlin, RJ. Disease of the salivary glands. In: Gorlin, RJ, Goldmann, HM, eds. Thomas’ Oral Pathology. St Louis: Mosby, 1970;9971003 Google Scholar
2 Sigismund, PE, Zenk, J, Koch, M, Schapher, M, Rudes, M, Iro, H. Nearly 3,000 salivary stones: some clinical and epidemiologic aspects. Laryngoscope 2015;125:1879–82Google Scholar
3 Marchal, F, Dulguerov, P. Sialolithiasis management: the state of the art. Arch Otolaryngol Head Neck Surg 2003;129:951–6Google Scholar
4 Schwarz, D, Kabbasch, C, Scheer, M, Mikolajczak, S, Beutner, D, Luers, JC. Comparative analysis of sialendoscopy, sonography, and CBCT in the detection of sialolithiasis. Laryngoscope 2015;125:1098–101Google Scholar
5 Hausegger, KW, Krasa, H, Pelzmann, W, Grasser, RK, Frisch, C, Simon, H. Sonography of the salivary glands [in German]. Ultraschall Med 1993;14:6874 Google Scholar
6 Katz, P, Hartl, DM, Guerre, A. Clinical ultrasound of the salivary glands. Otolaryngol Clin North Am 2009;42:9731000 Google Scholar
7 Zengel, P, Schrotzlmair, F, Reichel, C, Paprottka, P, Clevert, DA. Sonography: the leading diagnostic tool for diseases of the salivary glands. Semin Ultrasound CT MR 2013;34:196203 CrossRefGoogle ScholarPubMed
8 Gritzmann, N, Rettenbacher, T, Hollerweger, A, Macheiner, P, Hubner, E. Sonography of the salivary glands. Eur Radiol 2003;13:964–75Google Scholar
9 Orlandi, MA, Pistorio, V, Guerra, PA. Ultrasound in sialadenitis. J Ultrasound 2013;16:39 Google Scholar
10 Patel, NJ, Hashemi, S, Joshi, AS. Sonopalpation: a novel application of ultrasound for detection of submandibular calculi. Otolaryngol Head Neck Surg 2014;151:770–5Google Scholar
11 Rahmouni, A, Bargoin, R, Herment, A, Bargoin, N, Vasile, N. Color Doppler twinkling artifact in hyperechoic regions. Radiology 1996;199:269–71Google Scholar
12 Gao, J, Hentel, K, Rubin, JM. Correlation between twinkling artifact and color Doppler carrier frequency: preliminary observations in renal calculi. Ultrasound Med Biol 2012;38:1534–9Google Scholar
13 Jamzad, A, Setarehdan, SK. A novel approach for quantification and analysis of the color Doppler twinkling artifact with application in noninvasive surface roughness characterization: an in vitro phantom study. J Ultrasound Med 2014;33:597610 CrossRefGoogle ScholarPubMed
14 Hassani, H, Raynal, G, Spie, R, Daudon, M, Vallee, JN. Imaging-based assessment of the mineral composition of urinary stones: an in vitro study of the combination of hounsfield unit measurement in noncontrast helical computerized tomography and the twinkling artifact in color Doppler ultrasound. Ultrasound Med Biol 2012;38:803–10Google Scholar
15 Chelfouh, N, Grenier, N, Higueret, D, Trillaud, H, Levantal, O, Pariente, JL et al. Characterization of urinary calculi: in vitro study of “twinkling artifact” revealed by color-flow sonography. AJR Am J Roentgenol 1998;171:1055–60Google Scholar
16 Mansour, N, Stock, KF, Chaker, A, Bas, M, Knopf, A. Evaluation of parotid gland lesions with standard ultrasound, color duplex sonography, sonoelastography, and acoustic radiation force impulse imaging - a pilot study. Ultraschall Med 2012;33:283–8Google ScholarPubMed
17 Andrulli, S, Turrin, A, Bigi, MC, Ravani, P, Trinchieri, A, Locatelli, F. Colour Doppler twinkling in kidney stones: artefact or sign? NDT Plus 2010;3:151–4Google Scholar
18 Kamaya, A, Tuthill, T, Rubin, JM. Twinkling artifact on color Doppler sonography: dependence on machine parameters and underlying cause. AJR Am J Roentgenol 2003;180:215–22Google Scholar
19 Lee, JY, Kim, SH, Cho, JY, Han, D. Color and power Doppler twinkling artifacts from urinary stones: clinical observations and phantom studies. AJR Am J Roentgenol 2001;176:1441–5Google Scholar
20 Ripolles, T, Martinez-Perez, MJ, Vizuete, J, Miralles, S, Delgado, F, Pastor-Navarro, T. Sonographic diagnosis of symptomatic ureteral calculi: usefulness of the twinkling artifact. Abdom Imaging 2013;38:863–9Google Scholar
21 Shabana, W, Bude, RO, Rubin, JM. Comparison between color Doppler twinkling artifact and acoustic shadowing for renal calculus detection: an in vitro study. Ultrasound Med Biol 2009;35:339–50Google Scholar
22 Sutijono, D, Bomann, JS, Moore, CL, van Tonder, R. Twinkle twinkle little stone: utilizing color Doppler in emergency ultrasound diagnosis of a ureterovesicular stone. Crit Ultrasound J 2010;2:77–9Google Scholar
23 Tsao, TF, Tyan, YS, Kang, RJ, Kueng, MK, Lan, H, Su, YC et al. Correlation study of the strength of the color Doppler twinkling artifact with the roughness of the reflecting surface and the Doppler angles. J Med Ultrasound 2004;12:119–24Google Scholar
24 Aytac, SK, Ozcan, H. Effect of color Doppler system on the twinkling sign associated with urinary tract calculi. J Clin Ultrasound 1999;27:433–9Google Scholar
25 Wang, M, Li, J, Xiao, J, Shi, D, Zhang, K. Systematic analysis of factors related to display of the twinkling artifact by a phantom: an optimized investigation. J Ultrasound Med 2011;30:1449–57CrossRefGoogle ScholarPubMed
26 Turrin, A, Minola, P, Costa, F, Cerati, L, Andrulli, S, Trinchieri, A. Diagnostic value of colour Doppler twinkling artefact in sites negative for stones on B mode renal sonography. Urol Res 2007;35:313–17CrossRefGoogle Scholar