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Wegener's granulomatosis. First case report in Bahrain

Published online by Cambridge University Press:  29 June 2007

Ahmed Jamal ,
Reda Ali Ebrahim ,
Nabeel Tammam  and
Sungam Kanekar
Ahmed Jamal*
Affiliation:
Department of Otolaryngology, Salmaniya Medical Complex, Bahrain.
Reda Ali Ebrahim
Affiliation:
Department of Otolaryngology, Salmaniya Medical Complex, Bahrain.
Nabeel Tammam
Affiliation:
Department of Otolaryngology, Salmaniya Medical Complex, Bahrain.
Sungam Kanekar
Affiliation:
Department of Otolaryngology, Salmaniya Medical Complex, Bahrain.
*
Address for correspondence: Mr A. J. Jamal, Consultant ENT Surgeon and Head of ENT Department, Salmaniya Medical Complex, P.O. Box 12, Bahrain. Fax: 973 275612
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Abstract

Formerly a fatal condition, Wegener's granulomatosis is now treated with good results. Although the annual incidence of Wegener's granulomatosis in the general population is not known, most European and American studies revealed an incidence in the range of one for every 250,000 of the population. The estimated total population of Bahrain as of June 1997 is 586,110; here we report the first diagnosed case of Wegener's granulomatosis in Bahrain.

Our patient presented with epistaxis, and from the clinical features, the very high ESR, the operative, histopathological and the radiological findings, and a high index of suspicion we could confirm the diagnosis along with the appropriate immunological test (positive cANCA). Standard treatment with cytotoxic agents and corticosteroids has been used. On follow-up the patient has shown a progressive improvement in her clinical and laboratory parameters.

Keywords

Wegener's granulomatosisEpistaxis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 7 , July 1998 , pp. 664 - 666
Copyright
Copyright © JLO (1984) Limited 1998

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References

Ataman, M., Sarioglu, T., Shahidi, H., Gursel, B. (1994) Wegener's granulomatosis: case report and review of the literature. Rhinology 32: 92–97.Google ScholarPubMed
Geiger, W. J., Garrison, K. L., Losh, D. P. (1992) Wegener's granulomatosis. American family physician. 45: 191–196.Google ScholarPubMed
Kelly, W. N., Harris, E. D., Ruddy, S., Sledge, C. B. (1981) In Text Book of Rheumatology, 4th Edition, W. B. Saunders Company, Philadelphia, pp 1091–1094.Google Scholar
Kornblunt, A. D., Wolff, S. M., de Fries, H. O., Fauci, A. S. (1982) Wegener's granulomatosis – Symposium on granulomatous disorders of the head and neck. Otolaryngologic Cinics and North America 15: 673–682.Google Scholar
Lebovics, R. S., Hoffman, G. S., Leavit, R. Y., Kerr, G. S., Travis, W. D., Kammerer, W., Hallahan, C., Rottem, M., Fauci, A. S. (1992) The management of subglottic stenosis in patients with Wegener's granulomatosis. Laryngoscope 102: 1341–1345.CrossRefGoogle ScholarPubMed
Van der Woude, F. J., Rasmussen, N., Lobatto, S., Wikk, A., Permin, H., Van Es, L. A., Van der Gissen, M., Van der Hem, G. K., The, T. H. (1985) Autoantibodies to neutrophils and monocytes: a new tool for diagnosis and a marker of disease activity in Wegener's granulomatosis. Lancet 1: 425–429.CrossRefGoogle Scholar
Wilson, J. D., Braunwald, E., Isselbacher, K. J., Petersdorf, R. G., Martin, J. B., Fauci, A. S., Root, R. K. (1991) In Harrison's Principles of Internal Medicine, 12th Edition, McGraw-Hill Inc., New York, pp 1460–1461.Google Scholar