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Disclosing Conflicts of Interest in Clinical Research: Views of Institutional Review Boards, Conflict of Interest Committees, and Investigators

Published online by Cambridge University Press:  01 January 2021

Kevin P. Weinfurt ,
Joëlle Y. Friedman ,
Michaela A. Dinan ,
Jennifer S. Allsbrook ,
Mark A. Hall ,
Jatinder K. Dhillon  and
Jeremy Sugarman
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Extract

Investigator and institutional financial conflicts of interest have raised concerns about both the integrity of clinical research and protecting the rights and welfare of research participants. In response, professional groups and governmental bodies have issued guidance for managing conflicts of interest to minimize their potential untoward effects. Although a variety of approaches have been offered, a common protection is to disclose financial interests in research to potential research participants as part of the recruitment and informed consent process. This approach reinforces a basic norm of candor, ideally allowing potential research participants to evaluate whether financial interests should affect their decision to participate in research. Disclosure to potential research participants is viewed as an alternative to having regulators or research institutions limit or prohibit all financial interests in research, assuming that not all such interests are unacceptable.

Type
Independent
Information
Journal of Law, Medicine & Ethics , Volume 34 , Issue 3 , Fall 2006 , pp. 581 - 591
Copyright
Copyright © American Society of Law, Medicine and Ethics 2006

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