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Racial and Ethnic Categories in Biomedical Research: There is No Baby in the Bathwater

Published online by Cambridge University Press:  01 January 2021

Mildred K. Cho
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Extract

There are deep divides over the use of racial and ethnic categories in biomedical research and its application in both medical and non-medical contexts. On one side of a roughly described dividing line are practitioners who need to use every piece of information at their disposal to solve pressing, realworld problems in real time, such as making clinical diagnoses or identifying perpetrators of crime. On the other side are scientists and policy makers committed to meeting a scientific and social need for accuracy and thus trying to avoid miscategorization.

As Jay Cohn describes in this issue, medical practitioners in particular have used racial and ethnic categories to “enhance diagnostic and therapeutic precision.” He argues for retaining this practice. The plea, motivated by genuine concern for patients, is to avoid “throwing the baby out with the bathwater.” However, Cohn and others mischaracterize the nature of the debate. The argument is not about whether differences among populations exist, or even whether differences among “races” exist.

Type
Symposium
Information
Journal of Law, Medicine & Ethics , Volume 34 , Issue 3 , Fall 2006 , pp. 497 - 499
Copyright
Copyright © American Society of Law, Medicine and Ethics 2006

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References

Cohn, J., “The Use of Race and Ethnicity in Medicine: Letters from the African-American Heart Failure Trial,” Journal of Law, Medicine & Ethics 34, no. 3 (2006): 552–554.Google Scholar
Sankar, P. and Cho, M., “Toward a New Vocabulary of Human Genetic Variation,” Science 298 (2002): 1337–38.CrossRefGoogle Scholar
Cho, M. and Sankar, P., “Forensic Genetics: ELSI Beyond the Clinic,” Nature Genetics 36 (2004): S8–S12.CrossRefGoogle Scholar
Ossorio, P. and Duster, T., “Controversies in Biomedical, Behavioral, and Forensic Sciences,” American Psychologist 60 (2005): 115–128; Duster, T., “Lessons From History: Why Race and Ethnicity Have Played a Major Role in Biomedical Research,” Journal of Law, Medicine & Ethics 34, no. 3 (2006): 487–496.CrossRefGoogle Scholar
Lee, S. Mountain, J., and Koenig, B., “The Meanings of ‘Race’ in the New Genomics: Implications for Health Disparities Research,” Yale Journal of Health Policy, Law and Ethics 1 (2001): 33–75.Google Scholar
Linnaeus, C., Systema Naturae (Stockholm: Salvius, 1758): at 20–33.Google Scholar
Deniker, J., The Races of Man: An Outline of Anthropology and Ethnography (Paris: Charles Scribner, 1900): at 280.Google Scholar
Jorde, L. and Wooding, S., “Genetic Variation, Classification and ‘Race’,” Nature Genetics 36 (2004): S28–S33; Risch, N., “Categorization of Humans in Biomedical Research: Genes, Race, and Disease,” Genome Biology 3 (2003): 2007.1–.12; Rosenberg, N. et al., “Genetic Structure of Human Populations,” Science 298 (2002): 2381–85.CrossRefGoogle Scholar
Darwin, C., The Descent of Man, and Selection in Relation to Sex (London: John Murray, 1871): Chapter 7.Google Scholar
Jorde, L. and Wooding, S., “Genetic Variation, Classification and ‘Race’,” Nature Genetics 36 (2004): S28–S33.CrossRefGoogle Scholar
Keita, S. and Boyce, A., “‘Race’: Confusion about Zoological and Social Taxonomies, and Their Places in Science,” American Journal of Human Biology 13 (2001): 569–75.; Keita, S. et al., “Conceptualizing Human Variation,” Nature Genetics 36 (2004): S17–S20.CrossRefGoogle Scholar
American Heritage Dictionary of the English Language, 4th ed. (Boston: Houghton Mifflin Co., 2003).Google Scholar
See <http://dictionary.reference.com> (2005).+(2005).>Google Scholar
Rotimi, C., article of file with author.Google Scholar
Executive Office of the President, Office of Management and Budget, Standards for the Classification of Federal Data on Race and Ethnicity (Washington, D.C.: Government Printing Office, 1995).Google Scholar
American Anthropological Association, Response to OMB Directive 15: Race and Ethnic Standards for Federal Statistics and Administrative Reporting (Arlington, VA: 1997).Google Scholar
Hahn, R. Mulinare, J., and Teutsch, S., “Inconsistencies in Coding of Race and Ethnicity Between Birth and Death in US Infants: A New Look at Infant Mortality, 1983 through 1985,” JAMA 267 (1992): 3151–52.CrossRefGoogle Scholar
Lowe, A. Urquhart, A. Foreman, L., and Evett, I., “Inferring Ethnic Origin by Means of an STR Profile,” Forensic Science International 119 (2001): 17–22.CrossRefGoogle Scholar
Leech, K., “A Question in Dispute: The Debate About an ‘Ethnic’ Question in the Census,” in Runnymede Research Report (London: Runnymede Trust, 1989).Google Scholar
Wilson, J. et al., “Population Genetic Structure of Variable Drug Response,” Nature Genetics 29 (2001): 265–69.CrossRefGoogle Scholar
Otterness, D. et al., “Human Thiopurine Methyltransferase Pharmacogenetics: Gene Sequence Polymorphisms,” Clinical Pharmacology & Therapeutics 62 (1997): 60–73.CrossRefGoogle Scholar
Burroughs, V. Maxey, R., and Levy, R., “Individualized Pharmaceutical Treatment,” Journal of the National Medical Association 94 (2002): 1–26.Google Scholar
van Aken, J. Schmedders, M. Feuerstein, G., and Kollek, R., “Prospects and Limits of Pharmacogenetics: The Thiopurine Methyl Transferase (TPMT) Experience,” American Journal of Pharmacogenomics 3 (2003): 149–55.CrossRefGoogle Scholar
Cohn, , supra note 1.Google Scholar