Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2025-01-02T17:46:15.544Z Has data issue: false hasContentIssue false
  • English
  • Français

Porous Ca–P–O bio-glassceramics by loose-powder-sintering

Published online by Cambridge University Press:  31 January 2011

T. S. Chin ,
D. C. Wu ,
M. P. Hung  and
C. P. Wang
T. S. Chin*
Affiliation:
Department of Materials Science and Engineering, Tsing Hua University, Hsinchu, 300, Taiwan, Republic of China
D. C. Wu
Affiliation:
Department of Materials Engineering, Cheng Kung University, Tainan, 701, Taiwan, Republic of China
M. P. Hung
Affiliation:
Department of Materials Engineering, Cheng Kung University, Tainan, 701, Taiwan, Republic of China
C. P. Wang
Affiliation:
Department of Biology, Cheng Kung University, Tainan, 701, Taiwan, Republic of China
*
a) Address all correspondence to this author.
Get access

Abstract

Porous resorbable Ca–P–O glassceramic tooth roots based on calcium biphosphate were prepared by loose-powder-sintering then crystallization-annealing. The glass composition is, by weight, CaO/(CaO + P2O5) = 0.33. The sintering behavior of the glass can be described by a conventional viscous flow model. The resultant glassceramic has a pore size of 6 to 36 μm, depending on starting particle size and sintering temperature, while the pore size distribution is independent of sintering time. The flexural strength is 33 to 150 MPa depending mostly on crystallization-annealing treatment. The crystalline phases are β−Ca2P2O7 and CaP2O6. After being implanted into rabbits, these porous implants show remarkable biocompatibility and induce the ingrowth of new bone within 30 days. They are partly resorbed after 90 days and replaced by new bone. In spite of the original small porosity, the ingrowth of blood vessels and bone cells is abundantly seen after 90 days, due to enlarged pores produced by progressive resorption. This glassceramic is a good candidate for resorbable tooth and bone implants. The loose-powder-sintering technique resulting in intricate bulk shapes with controllable pore size distribution and good machinability as well as adjustable mechanical strength hence is a powerful technique for the preparation of porous glassceramics.

Type
Articles
Information
Journal of Materials Research , Volume 11 , Issue 4 , April 1996 , pp. 962 - 969
Copyright
Copyright © Materials Research Society 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Hench, L. L., Science 208, 826 (1980).Google Scholar
2.Hulbert, S. F. and Hench, L. L., Ceram. Int. 8, 131 (1982).CrossRefGoogle Scholar
3. See, for instance, more recent articles in conference proceedings, such as in Tissue-inducing Biomaterials, edited by Cima, L. G. and Ron, E. S. (Mater. Res. Soc. Symp. Proc. 252, PA, 1992), and An Introduction to Bioceramics, edited by L. L. Hench and J. Wilson (World Scientific, Singapore, 1993).Google Scholar
4.Adair, P. J. and Grossman, D. G., Int. J. Period. Restor. Dent. 2, 33 (1984).Google Scholar
5.Hench, L. L., Splinter, R. J., Allen, W. C., and Greenlee, T. K. Jr., Biomed. Mater. Symp., Trans. 2, 117 (1972).Google Scholar
6.Blencke, B. A., Bromer, H., and Deutscher, K. K., J. Biomed. Mater. Res. 12, 307 (1978).Google Scholar
7.Hulbert, S. F., Young, F. A., Mattews, R. S., Klawitter, J.J., Talbery, C. D., and Stelling, F. H., J. Biomed. Mater. Res. 4, 433 (1970).CrossRefGoogle Scholar
8.Klawitter, J. J. and Hulbert, S. F., Biomed. Mater. Symp. 2, 161 (1972).Google Scholar
9.Koneman, J. B., Rybicki, E. F., Klawitter, J.J., and Weinstein, A. M., Biomed. Mater. Res. Symp., Trans. 1, 139 (1977).Google Scholar
10.Hench, L. L. and Ethridge, E. C., Biomaterials, An Interfacial Approach (Academic Press, New York, 1982), p. 69.Google Scholar
11.Dudrova, E. and Salak, A., Powder Metall. Int. 8, 122 (1976).Google Scholar
12.Akechi, K. and Hara, Z., in Sintering-New Development, edited by Ristic, M. M. (Elsevier Sci. Pub. Co., Amsterdam, 1979), pp. 67–75.Google Scholar
13.Chin, T. S., Wu, D. C., Liu, H. S., Hung, M. P., and Wang, C. P., in Tissue-inducing Biomaterials, edited by Cima, Linda G. and Ron, Eyal S. (Mater. Res. Soc. Symp. Proc. 252, Pittsburgh, PA, 1992), pp. 103–108.Google Scholar
14.Zagar, L., in Sintering-New Development, edited by Ristic, M. M. (Elsevier Sci. Pub. Co., Amsterdam, 1979), pp. 57–64; V. A. Ivenson, Poroshkova Mettalurgiya 4, 20 (1970).Google Scholar
15.Monma, H., Yogyo-Kyokai-Shi 95, 814 (1987).CrossRefGoogle Scholar
16.de Groot, K. in Biocompatibility of clinical implant Materials, edited by Williams, D. F. (CRC Press, Boca Raton, FL, 1981), Vol. 1, p. 199.Google Scholar