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The study of ultrasound-assisted extraction of flavonoids from Polygonum cuspidatum Sieb. et Zucc.

Published online by Cambridge University Press:  29 April 2019

Weiwei Jia ,
Zhenbin Chen ,
Yingyu Zhao ,
Ke Li ,
Brandon Tichnell ,
Zhenghua Tang ,
Juan M. Ruso  and
Zhen Liu Open the ORCID record for Zhen Liu [Opens in a new window]
Weiwei Jia
Affiliation:
College of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China; and State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, China
Zhenbin Chen*
Affiliation:
College of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China; and State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, China
Yingyu Zhao
Affiliation:
College of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China; and State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, China
Ke Li*
Affiliation:
College of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China; and State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, China
Brandon Tichnell
Affiliation:
Department of Physics and Engineering, Frostburg State University, Frostburg, Maryland 21532, USA
Zhenghua Tang
Affiliation:
Guangzhou Key Laboratory for Surface Chemistry of Energy Materials, New Energy Research Institute, School of Environment and Energy, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou 5100067, China; and Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution Control, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou 510006, China
Juan M. Ruso
Affiliation:
Soft Matter and Molecular Biophysics Group, Department of Applied Physics, University of Santiago de Compostela, Santiago de Compostela 15782, Spain
Zhen Liu*
Affiliation:
Department of Physics and Engineering, Frostburg State University, Frostburg, Maryland 21532, USA
*
a)Address all correspondence to these authors. e-mail: zhenbinchen@163.com
b)e-mail: zhenliu8@gmail.com
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Abstract

In this work, flavonoids in Polygonum cuspidatum Sieb. et Zucc. were extracted by ultrasound-assisted methodology and determined by ultraviolet–visible spectrophotometry. After that, extraction conditions were optimized by the single fact investigation, the central composite design, and response surface methodology (RSM) in turn. The results showed the optimal values of ethanol concentration, solid–liquid ratio, extraction temperature, extraction time, ultrasonic power, and number of extraction times were 60%, 1:20 (g/mL), 45 °C, 34 min; 80 W, and 5, respectively. The extraction ratio of flavonoids could be as high as 94.50%. The influence order of each factor was ultrasonic power > extraction time > extraction temperature > ethanol concentration. The results also showed that the experimental value was close to the predicted value (94.49%) of the established model by RSM, which proved that the established model was reasonable. The thermodynamic results showed that the extraction process was endothermic and could proceed spontaneously.

Keywords

biologicalchemical compositionethanol
Type
Invited Paper
Information
Journal of Materials Research , Volume 34 , Issue 19: Focus Issue: Thermodynamics of Complex Solids , 14 October 2019 , pp. 3254 - 3262
Copyright
Copyright © Materials Research Society 2019 

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References

Bralley, E.E., Greenspan, P., Hargrove, J.L., Wicker, L., and Hartle, D.K.: Topical anti-inflammatory activity of Polygonum cuspidatum extract in the TPA model of mouse ear inflammation. J. Inflamm. 5, 1 (2008).CrossRefGoogle ScholarPubMed
Huang, G., Gao, Y., Wu, Z., Yang, Y., Huang, D., Chen, W., and Sun, N.: Chemical constituents from Polygonum capitatum Buch-Ham. ex D. Don. Biochem. Syst. Ecol. 59, 8–11 (2015).CrossRefGoogle Scholar
Tadhani, M.B., Patel, V.H., and Subhash, R.: In vitro antioxidant activities of Stevia rebaudiana leaves and callus. J. Food Compos. Anal. 20, 323–329 (2007).CrossRefGoogle Scholar
Muanda, F.N., Soulimani, R., Diop, B., and Dicko, A.: Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves. LWT - Food Sci. Technol. 44, 1865–1872 (2011).CrossRefGoogle Scholar
Yadav, S.K. and Guleria, P.: Steviol glycosides from Stevia: Biosynthesis pathway review and their application in foods and medicine. Crit. Rev. Food Sci. 52, 988–998 (2012).CrossRefGoogle Scholar
Wölwer-Rieck, U.: The leaves of Stevia rebaudiana (Bertoni), their constituents and the analyses thereof: A review. J. Agric. Food Chem. 60, 886–895 (2012).CrossRefGoogle ScholarPubMed
Wang, K.J., Li, H.J., and Zhao, Y.M.: Advances on synthesis of flavonoid glycosides. Chem. Bull. 68, 490–496 (2005).Google Scholar
Iinuma, M., Tanaka, T., Ito, K., and Mizuno, M.: Flavonoids syntheses. V. Synthesis of flavonoids with three hydroxy and four methoxy groups and their spectral properties. Chem. Pharm. Bull. 35, 660–667 (1987).CrossRefGoogle Scholar
Barros, A.I. and Silva, A.M.S.: Efficient synthesis of nitroflavones by cyclodehydrogenation of 2′-hydroxychalcones and by the Baker-Venkataraman method. Monatsh. Chem. 137, 1505–1528 (2006).CrossRefGoogle Scholar
Dreyer, D.L., Tabata, S., and Horowitz, R.M.: Flavonoids of citrus-VIII: Synthesis of limocitrol, limocitrin and spinacetin. Tetrahedron 20, 2977–2983 (1964).CrossRefGoogle Scholar
Caunii, A., Pribac, G., Grozea, I., Gaitin, D., and Samfira, I.: Design of optimal solvent for extraction of bio–active ingredients from six varieties of Medicago sativa. Chem. Cent. J. 6, 123 (2012).CrossRefGoogle ScholarPubMed
Gao, Z., Huang, K., Yang, X., and Xu, H.: Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochim. Biophys. Acta, Gen. Subj. 1472, 643–650 (1999).CrossRefGoogle ScholarPubMed
Wang, L., Yang, B., Du, X., and Yi, C.: Optimisation of supercritical fluid extraction of flavonoids from Pueraria lobata. Food Chem. 108, 737–741 (2008).CrossRefGoogle ScholarPubMed
Huang, W., Xue, A., Niu, H., Jia, Z., and Wang, J.: Optimised ultrasonic-assisted extraction of flavonoids from Folium eucommiae and evaluation of antioxidant activity in multi-test systems in vitro. Food Chem. 114, 1147–1154 (2009).CrossRefGoogle Scholar
Novak, I., Janeiro, P., Seruga, M., and Oliveira-Brett, A.M.: Ultrasound extracted flavonoids from four varieties of Portuguese red grape skins determined by reverse-phase high-performance liquid chromatography with electrochemical detection. Anal. Chim. Acta 630, 107–115 (2008).CrossRefGoogle ScholarPubMed
Chen, L., Yang, M., Mou, H., and Kong, Q.: Ultrasound-assisted extraction and characterization of anthocyanins from purple corn bran. J. Food Process. Preserv. 42, 1 (2017).Google Scholar
Hartonen, K., Parshintsev, J., Sandberg, K., Bergelin, E., Nisula, L., and Riekkola, M.: Isolation of flavonoids from aspen knotwood by pressurized hot water extraction and comparison with other extraction techniques. Talanta 74, 32–38 (2007).CrossRefGoogle ScholarPubMed
Vrchotová, N. and Šerá, B.: Allelopathic properties of knotweed rhizome extracts. Plant Soil Environ. 54, 301–303 (2008).CrossRefGoogle Scholar
Zhao, H., Yang, Y., and Li, L.: The pilot study of bamboo leaves flavonoids extraction by alkaline solution. Shandong Chem. Ind. 44, 62 (2015).Google Scholar
Wang, L., Li, D., Bao, C., You, J., Wang, Z., Shi, Y., and Zhang, H.: Ultrasonic extraction and separation of anthraquinones from Rheum palmatum L. Ultrason. Sonochem. 15, 738–746 (2008).CrossRefGoogle ScholarPubMed
Wang, L. and Weller, C.L.: Recent advances in extraction of nutraceuticals from plants. Trends Food Sci. Technol. 17, 300–312 (2006).CrossRefGoogle Scholar
Zheng, L.L., Wen, G., Yuan, M.Y., and Gou, F.: Ultrasound-assisted extraction of total flavonoids from corn silk and their antioxidant activity. J. Chem. 2016, 1–5 (2016).Google Scholar
Garcia-Castello, E.M., Rodriguez-Lopez, A.D., Mayor, L., Ballesteros, R., Conidi, C., and Cassano, A.: Optimization of conventional and ultrasound assisted extraction of flavonoids from grapefruit (Citrus paradisi L.) solid wastes. LWT - Food Sci. Technol. 64, 1114–1122 (2015).CrossRefGoogle Scholar
Wang, B., Qu, J., Luo, S., Feng, S., Li, T., Yuan, M., Huang, Y., Liao, J., Yang, R., and Ding, C.: Optimization of ultrasound-assisted extraction of flavonoids from olive (Olea europaea) leaves, and evaluation of their antioxidant and anticancer activities. Molecules 23, 2513 (2018).CrossRefGoogle ScholarPubMed
Krishnan, R.Y. and Rajan, K.S.: Microwave assisted extraction of flavonoids from Terminalia bellerica: Study of kinetics and thermodynamics. Sep. Purif. Technol. 157, 169–178 (2016).CrossRefGoogle Scholar
Zhang, C.X., Hu, X.L., Yue, H., Lu, L., and Lu, J.H.: Extract of flavones from ginkgo leaves. Chem. Res. Appl. 8, 454–456 (2001).Google Scholar
Zhu, J.H.: Study on the extraction and separation of flavonoids from licorice. Chin. Pharmaceut. 19, 88–90 (2010).Google Scholar
Tian, C.R. and Li, W.: Studies on the alcohol extracting technology of flavonoids in Ginkgo biloba leaves. Acta Bot. Boreali-Occidentalia Sin. 3, 556–561 (2001).Google Scholar
Chen, C.J., Huang, K.Y., Li, D.L., and Chong, C.L.: Research review on the extracting methods of flavonoids from plants. Biomass Chem. Eng. 5, 42–46 (2007).Google Scholar
Rodríguez-Pérez, C., Gilbert-López, B., Mendiola, J.A., Quirantes-Piné, R., Segura-Carretero, A., and Ibáñez, E.: Optimization of microwave-assisted extraction and pressurized liquid extraction of phenolic compounds from Moringa oleifera leaves by multiresponse surface methodology. Electrophoresis 37, 1938–1946 (2016).CrossRefGoogle ScholarPubMed
Yang, L., Cao, Y.L., Jiang, J.G., Lin, Q.S., Chen, J., and Zhu, L.: Response surface optimization of ultrasound-assisted flavonoids extraction from the flower of Citrus aurantium L. var. amara. Engl. J. Sep. Sci. 33, 1349–1355 (2010).Google ScholarPubMed
Ho, U.T.N., Tran, L.T.M., Dinh, A.Q., and An, T.N.: Response surface optimization of ethanolic extraction of antioxidants from artichoke leaves. J. Food Process. Preserv. 39, 1036–1044 (2014).CrossRefGoogle Scholar
Bai, X.L., Yue, T.L., Yuan, Y.H., and Zhang, H.W.: Optimization of microwave-assisted extraction of polyphenols from apple pomace using response surface methodology and HPLC analysis. J. Sep. Sci. 33, 3751–3758 (2010).CrossRefGoogle ScholarPubMed
Pilkington, J.L., Preston, C., and Gomes, R.L.: Comparison of response surface methodology (RSM) and artificial neural networks (ANN) towards efficient extraction of artemisinin from Artemisia annua. Ind. Crops Prod. 58, 15–24 (2014).CrossRefGoogle Scholar
Belwal, T., Dhyani, P., Bhatt, I.D., Belwal, T., Dhyani, P., Bhatt, I.D., Rawal, R.S., and Pande, V.: Optimization extraction conditions for improving phenolic content and antioxidant activity in Berberisasiatica fruits using response surface methodology (RSM). Food Chem. 207, 115–124 (2016).CrossRefGoogle Scholar
Maran, J.P., Manikandan, S., Nivetha, C.V., and Dinesh, R.: Ultrasound assisted extraction of bioactive compounds from Nephelium lappaceum L. fruit peel using central composite face centered response surface design. Arabian J. Chem. 10, S1145–S1157 (2017).CrossRefGoogle Scholar
Ilaiyaraja, N., Likhith, K.R., Babu, G.R.S., and Khanum, F.: Optimisation of extraction of bioactive compounds from Feronia limonia (wood apple) fruit using response surface methodology (RSM). Food Chem. 173, 348–354 (2015).CrossRefGoogle Scholar
Li, H.J. and Sun, J.F.: The determination of flavonoids in Lamiophlomis rotate and its preparations. Lishizhen Med. Mater. Med. Res. 24, 1018–1019 (2013).Google Scholar
Mason, T.J., Paniwnyk, L., and Lorimer, J.P.: The uses of ultrasound in food technology. Ultrason. Sonochem. 3, S253–S260 (1996).CrossRefGoogle Scholar
Wang, J., Sun, B., Cao, Y., Tian, Y., and Li, X.: Optimisation of ultrasound-assisted extraction of phenolic compounds from wheat bran. Food Chem. 106, 804–810 (2008).CrossRefGoogle Scholar
Jing, C.L., Dong, X.F., and Tong, J.M.: Optimization of ultrasonic-assisted extraction of flavonoid compounds and antioxidants from Alfalfa using response surface method. Molecules 20, 15550–15571 (2015).CrossRefGoogle ScholarPubMed
Zhang, G., He, L., and Hu, M.: Optimized ultrasonic-assisted extraction of flavonoids from Prunella vulgaris L. and evaluation of antioxidant activities in vitro. Innov. Food Sci. Emerg. 12, 18–25 (2011).CrossRefGoogle Scholar
Hemwimol, S., Pavasant, P., and Shotipruk, A.: Ultrasound-assisted extraction of anthraquinones from roots of Morinda citrifolia. Ultrason. Sonochem. 13, 543–548 (2006).CrossRefGoogle ScholarPubMed
Hu, A., Li, L., Zheng, J., Lu, J., Meng, X., Liu, Y., and Rehman, R.U.: Different-frequency ultrasonic effects on properties and structure of corn starch. J. Sci. Food Agric. 94, 2929–2934 (2014).CrossRefGoogle ScholarPubMed
Yuan, J., Huang, J., Wu, G., Tong, J., Xie, G., Duan, J.A., and Qin, M.: Multiple responses optimization of ultrasonic-assisted extraction by response surface methodology (RSM) for rapid analysis of bioactive compounds in the flower head of Chrysanthemum morifolium Ramat. Ind Crop Prod 74, 192–199 (2015).CrossRefGoogle Scholar
Shin, Y., Liu, R.H., Nock, J.F., Holliday, D., and Watkins, C.B.: Temperature and relative humidity effects on quality, total ascorbic acid, phenolics and flavonoid concentrations, and antioxidant activity of strawberry. Postharvest Biol. Technol. 45, 349–357 (2007).CrossRefGoogle Scholar
Ebrahimzadeh, M.A., Pourmorad, F., and Bekhradnia, A.R.: Iron chelating activity, phenol and flavonoid content of some medicinal plants from Iran. Afr. J. Biotechnol. 7, 3188–3192 (2008).Google Scholar
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