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Surface treatment of titanium by anodization and iron deposition: mechanical and biological properties

Published online by Cambridge University Press:  26 May 2020

Murali Krishna Duvvuru ,
Lupeng Wu ,
Nicole S. Lin ,
Tao Xu  and
Sahar Vahabzadeh
Murali Krishna Duvvuru
Affiliation:
Department of Mechanical Engineering, Northern Illinois University, DeKalb, Illinois 60115, USA
Lupeng Wu
Affiliation:
Department of Mechanical Engineering, Northwestern University, Evanston, Illinois 60208, USA
Nicole S. Lin
Affiliation:
Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, USA
Tao Xu
Affiliation:
Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, USA
Sahar Vahabzadeh*
Affiliation:
Department of Mechanical Engineering, Northern Illinois University, DeKalb, Illinois 60115, USA
*
a)Address all correspondence to this author. e-mail: svahabzadeh@niu.edu
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Abstract

Surface modification of titanium and titanium alloys is a common method to improve anchoring of bone tissue and implants in hard tissue engineering applications. In the current work, a combination of chemical and physical methods (anodization and physical vapor deposition) was used to roughen the titanium surface and deposit iron (Fe) on the surface of titanium at different thicknesses. The optimized thickness of 100 Å was selected for mechanical and biological characterization. We found that anodization increases the surface roughness of Ti from 21 ± 0 to 229 ± 9 nm, whereas Fe deposition does not change it significantly. Our results also showed that surface modification of Ti by anodization increases the proliferation of osteosarcoma cells at both time points, whereas Fe-deposited samples showed the lowest cellular activity. These results suggest that Fe-deposited Ti implants may be suitable candidates for patients with osteosarcoma, as the proliferation of malignant cells decreases in the presence of Fe.

Keywords

biomaterialTibone
Type
Article
Information
Journal of Materials Research , Volume 35 , Issue 10 , 28 May 2020 , pp. 1290 - 1297
Copyright
Copyright © Materials Research Society 2020

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