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Diagnostic Problems in Pre-Senile Dementia Illustrated by a Case of Alzheimer's Disease Proven Histologically During Life

Published online by Cambridge University Press:  08 February 2018

Denis Parr
Denis Parr*
Affiliation:
Department of Psychiatry, St. George's Hospital
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Extract

Maladjustment at work is not synonymous with sickness, but when a middle-aged man becomes grossly inefficient in a job at which he has previously excelled, the chances are that he is ill. This paper describes such a case, and the investigations that led to the diagnosis by cortical biopsy of Alzheimer's Disease. So far as is known, this is the first recorded instance in this country of Alzheimer's Disease being diagnosed histologically during life. Apart from its interest as a clinical curiosity, however, this case illustrates some practical problems often arising in the assessment of this type of patient, which can be as difficult and responsible a task as any that the psychiatrist has to undertake.

Type
Original Articles
Information
Journal of Mental Science , Volume 101 , Issue 423 , April 1955 , pp. 387 - 390
Copyright
Copyright © Royal College of Psychiatrists, 1955 

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