Hostname: page-component-cd9895bd7-hc48f Total loading time: 0 Render date: 2024-12-28T21:52:26.389Z Has data issue: false hasContentIssue false
  • English
  • Français

An Evaluation of Chlorpromazine (“Largactil”) in Psychiatry

Published online by Cambridge University Press:  08 February 2018

F. B. E. Charatan
F. B. E. Charatan*
Affiliation:
Cane Hill Hospital, Coulsdon, Surrey
Get access Rights & Permissions [Opens in a new window]

Extract

During the last two years, considerable interest has been aroused in the use of chlorpromazine in psychiatry, particularly on the Continent. A full report on the pharmacological properties of the drug appeared in 1953 (Courvoisier et al.), and a short account was given in the first paper describing the effects of chlorpromazine in the treatment of mentally ill patients in this country (Anton-Stephens, 1954). In that study, the drug was administered to patients in several diagnostic categories. A reduction in the disturbed behaviour of excited patients was observed, but considerable variation in response to the drug occurred. Small doses orally were ineffective, and a parenteral daily dosage of 200 mgm. was initially required to produce a clinical response.

Type
Original Articles
Information
Journal of Mental Science , Volume 100 , Issue 421 , October 1954 , pp. 882 - 893
Copyright
Copyright © Royal College of Psychiatrists, 1954 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anton-Stephens, D., J. Ment. Sci., 1954, 100, 543.CrossRefGoogle Scholar
Arnold, O. H., Hift, St., and Solms, W., Wiener Med. Wchnschr., 1952, 48, 964.Google Scholar
Idem , ibid, 1953, 31, 563.Google Scholar
Bensoussan, P-A., and Klein, F., Ann. Méd-Psych., 1953, 4, 529.Google Scholar
Berard, E., Personal communication, 1954.Google Scholar
Cossa, P., Bougeant, H., and Lombard, A., Ann. Méd-Psych., 1953, 3, 628.Google Scholar
Courvoisier, S., Fournel, J., Ducrot, R., Kolsky, M., and Kretschet, P., Arch. Int. Pharmacodyn., 1953, 3–4, 305.Google Scholar
Delay, J., Deniker, P., and Harl, J. M., Ann. Méd-Psych., 1952, 2, 267.Google Scholar
Idem and Grasset, A., Ibid, 1952, 3, 398.Google Scholar
Deschamps, A., Presse Méd., 1952, 60, 944.Google Scholar
Idem and Cadoret, M., Ibid, 1953, 61, 878.Google Scholar
Ey, H., and Berard, E., L'Evolution Psychiatrique, 1952, 4, 661 (Oct.-Dec.).Google Scholar
Idem and Deschamps, A., Pratique de l'Hibernothérapie, 1954, 181. Paris: Masson et Cie.Google Scholar
Friend, D. G., and Cummins, J. F., J.A.M.A., 1953, 153, 480.Google Scholar
Gillespie, R. D., J. Neurol. and Psychiat., 1939, 2, 45.CrossRefGoogle Scholar
Hamon, J., Paraire, J., and Velluz, J., Ann. Méd-Psych., 1952, 1, 331.Google Scholar
Lehmann, H. E., and Hanrahan, G. E., A.M.A. Arch. Neurol. Psychiat., 1954, 71, 227.Google Scholar
Staeheun, J. E., and Kielholtz, P., Schweitz. Med. Wchnschr., 1953, 25, 581.Google Scholar
Terzian, H., Pass, di Neurol. Veget., 1952, 4–5, 211.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.