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Some Effects of Methyl-Phenidate (Ritalin) And Amphetamine on Normal and Leucotomized Monkeys

Published online by Cambridge University Press:  09 January 2018

J. Cole  and
P. Glees
J. Cole
Affiliation:
University Laboratory of Physiology, Oxford
P. Glees
Affiliation:
University Laboratory of Physiology, Oxford
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Extract

In a previous report (Cole and Glees, 1956) on methyl-phenidate (Ritalin) as an antagonist to reserpine (Serpasil) in monkeys we referred to a similar effect produced by amphetamine. Following up this work we have now studied and compared the effects of methyl-phenidate and amphetamine when given separately without reserpine to normal and leucotomized monkeys.

Type
Original Articles
Information
Journal of Mental Science , Volume 103 , Issue 431 , April 1957 , pp. 406 - 417
Copyright
Copyright © Royal College of Psychiatrists, 1957 

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References

Cole, J., and Glees, P., “Ritalin as an antagonist to Reserpine in monkeys”, Lancet, 1956, i, 338.CrossRefGoogle Scholar
Collins, E. H., “Localization of an experimental hypothalamic and midbrain syndrome simulating sleep”, J. Comp. Neurol., 1954, 100, 661–98.Google Scholar
Feldberg, W., “Pattern of excitation and inhibition produced by injection of substances into the cerebral ventricle of the conscious cat”, Abstracts of Reviews, XXth International Physiological Congress, Brussels, 1956, 18.Google Scholar
Idem , and Sherwood, S. L., “Injections of bulbocapnine into the cerebral ventricles of cat”, Brit. J. Pharmacol., 1955, 10, 371–4.Google Scholar
Ferguson, J. T., “Treatment of Reserpine-induced depression with a new analeptic: ∗∗∗phenidylate”, Ann. N.Y. Acad. Sci., 1955, 61, 101–7.Google Scholar
French, J. D., Peon, R. H, and Livingston, R. P., “Projections from cortex to cephalic brain stem (reticular formation) in monkey”, J. Neurophysiol., 1955, 18, 74–95.Google Scholar
Freudenberg, R., Glees, P., Obrador, S., Foss, B., and Williams, M., “Experimental studies of frontal lobe functions in monkeys in relation to leucotomy”, J. Ment. Sci., 1950, 96, 143–56.Google Scholar
Fulton, J. F., Functional localization in the frontal lobes and cerebellum, 1949. Oxford: Clarendon Press.Google Scholar
Gellhorn, E., “Analysis of anatomic hypothalamic functions in the intact organism”, Neurology, 1956, 6, 335–43.CrossRefGoogle Scholar
Glees, P., “The interrelation of the strio-pallidum and the thalamus in the macaque monkey”, Brain, 1945, 68, 331–46.Google Scholar
Idem , Cole, J., Whitty, C. W. M., and Cairns, H., “The effects of lesions in the cingular gyrus and adjacent areas in monkeys”, J. Neurol. Neurosurg. and Psychiat., 1950, 13, 178–90.Google Scholar
Idem , Meyer, A., and Meyer, M., “Terminal degeneration in the frontal cortex of the rabbit following the interruption of afferent fibres”, J. Anat., 1946, 80, 101–6.Google Scholar
Meier, R., Gross, F., and Tripod, J., “Ritaline, eine neuartige synthetische Verbindung mit spezifischer zentralerregender Wirkungskomponente”, J. Klin. Wschr., 1954, 32, 445–50.Google Scholar
Partridge, M. W., Prefrontal Leucotomy, 1950. Oxford: Blackwell.Google Scholar
Shepherd, M., “Reserpine: problems associated with the use of a so-called Tranquillizing Agent’ ”, Proc. roy. Soc. Med., 1956, 49, 849–52.Google Scholar
Wall, P. D., Glees, P., and Fulton, J. F., “Cortifugal connexions of posterior orbital surface in Rhesus monkey”, Brain, 1951, 74, 66–71.Google Scholar
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