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Sulfosin Therapy in Schizophrenia

Published online by Cambridge University Press:  19 February 2018

Louis Minski
Louis Minski*
Affiliation:
Maudsley Hospital
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Extract

Sulfosin was first introduced by Schroeder (1) in the treatment of general paralysis and other syphilitic infections of the nervous system, and later its use was extended to the treatment of schizophrenia. He stated that the results were encouraging, and that this method of treatment was worthy of an extended trial. Loberg (2) treated 100 schizophrenic patients with sulfosin, and of these 49 had remissions in varying degrees. In a later report (3) he stated he had treated 135 patients, of whom 62 improved but only 12 had permanent remissions. Marcuse and Kallmann (4) treated 46 patients, 16 of whom were improved; Salinger (5) treated 16 patients, of whom 2 had remissions and 14 were unchanged.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 77 , Issue 319 , October 1931 , pp. 792 - 803
Copyright
Copyright © Royal College of Psychiatrists, 1931 

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References

1 Schroeder, K., Lancet, 1929, ii, p. 1081; “Om Sulfosin behandlung av Schizophreni,” Ugeskr. Laeg., 1929, p. 519; “Über Schwefelbehandlung der Dementia paralytica usw.,” Klin. Wochenschr., 1927, p. 2189.CrossRefGoogle Scholar
2 Loberg, , Karl, , “Sulfosinbehandlung der Dementia Præcox,” Zeitschr. f. d. ges. Neurol. und Psychiat., 1929, cxxiii, p. 449.Google Scholar
3 Idem , Irish Journ. Med. Sci., 1930, p. 285.Google Scholar
4 Marcuse, und Kallmann, , “Zur Sulfosinbehandlung der Paralyse und Schizophrenie,” Der Nervenarzt, 1929, ii, H. 3.Google Scholar
5 Salinger, F., “Über Sulfosinbehandlung Schizophrener Psychosen,” Arch. f. Psychiat., 1929, lxxxvi, p. 723.CrossRefGoogle Scholar
6 Letter dated March 23, 1931.Google Scholar
7 Campanacci, D., and Balducci, R., “Hypoglykämische Wirkung des Schwefels,” Klin. Wochenschr., No. 5, pp. 2166–2167.CrossRefGoogle Scholar
8 Foncin, R., and Sandor, J., “Lowering of Glycæmia by Injections of Sulphur: Contribution to Study of Colloidal Shock,” Compt. rend. Soc. de Biol., September 21, 1926, xcv, pp. 697–700; abs. Journ. Amer. Med. Assoc., November 27, 1926, lxxxvii, p. 1869.Google Scholar
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