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Published online by Cambridge University Press: 10 April 2007
Neuroleptic malignant syndrome (NMS) is a severe and potentially lethal complication of antipsychotic medication. Differential diagnosis is extremely important because severe catatonia, which has some simi??larities to NMS, may also be lethal but requires antipsychotic treatment. We present a case report of a 62-year-old woman who was admitted to hospital for differential diagnosis of NMS and suffered from severe haloperidol intoxication, which complicated the diagnostic evaluation. Further differential diagnostic aspects are summarised and their therapeutic implications are outlined.