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Evaluation of the dose received by ovaries in the treatment of a desmoid tumour presenting in the lower extremity using intensity-modulated radiotherapy tomotherapy

Published online by Cambridge University Press:  23 January 2017

Songül Barlaz Us  and
Öztun Temelli
Songül Barlaz Us*
Affiliation:
Department of Radiation Oncology, Faculty of Medicine, Mersin Universitesi, Çiftlikköy Kampüsü, Mersin, Turkey
Öztun Temelli
Affiliation:
Department of Radiation Oncology, Faculty of Medicine, Inönü University, Elazğ Yolu Üzeri, Malatya, Turkey
*
Correspondence to: Songül Barlaz Us, Department of Radiation Oncology, Faculty of Medicine, Mersin Universitesi, Çiftlikköy Kampüsü, Mersin, Mersin 33000, Turkey. Tel: +90 505 895 5284. E-mail: barlaz@gmail.com
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Abstract

Background

Desmoid tumour is a rare neoplasm occurring intra- and extra-abdominally.

Method

In this study, a lower extremity desmoid tumour located close to the ovaries was irradiated with tomotherapy after surgery in a 16-year-old female patient. 30 fractions defined for delivery of 54 Gy were administered to the patient.

Result

The planning target volume and organs at risk doses were evaluated and the ovary doses were discussed for fertility.

Conclusion

The patient tolerated the radiotherapy well. During radiotherapy, only grade 1 skin toxicity occurred.

Keywords

desmoid tumourIMRTovarytomotherapy
Type
Case Study
Information
Journal of Radiotherapy in Practice , Volume 16 , Issue 1 , March 2017 , pp. 109 - 112
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Copyright
© Cambridge University Press 2017 

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References

1. Karabulut, S, Keskin, S, Ekenel, M et al. The clinical effect of a positive surgical margin and adjuvant postoperative radiotherapy in the treatmenT of resectable desmoid tumors. Mol Clin Oncol 2013: 1061–1064.CrossRefGoogle ScholarPubMed
2. Nuyttens, J J, Rust, P F, Thomas, C R Jr et al. Surgery versus radiation therapy for patients with aggressive fibromatosis or desmoid tumors. A comparative review of 22 articles. Cancer 2000; 88: 1517–1523.3.0.CO;2-9>CrossRefGoogle ScholarPubMed
3.RTOG Protocol. https://en.wikibooks.org/wiki/Radiation_Oncology/Toxicity/Hansen. Accessed on September 2015.Google Scholar
4. Paddick, I. A simple scoring ratio to index the conformity of radiosurgical treatment plans. J Neurosurg 2000; 93 (3): 219–222.CrossRefGoogle ScholarPubMed
5. Pathak, P, Vashisht, S. A quantitative analysis of intensity-modulated radiation therapy plans and comparison of homogeneity indices for the treatment of gynecological cancers. J Med Phys 2013; 38: 67–73.CrossRefGoogle ScholarPubMed
6. Meirow, D, Nugent, D. The effects of radiotherapy and chemotherapy on female reproduction. Hum Reprod Update 2001; 7 (6): 535–543.CrossRefGoogle ScholarPubMed
7. Chemaitilly, W, Mertens, A C, Mitby, P et al. Sklar acute ovarian failure in the childhood cancer survivor study. J Clin Endocrinol Metab 2006; 91 (5): 1723–1728.CrossRefGoogle ScholarPubMed
8. Stroud, J S, Mutch, D, Rader, J et al. Effects of cancer treatment on ovarian function. Fertil Steril 2009; 92 (2): 417–427.CrossRefGoogle ScholarPubMed
9. Green, D M, Yakar, D, Brecher, M L et al. Ovarian function in adolescent women following successful treatment for non-Hodgkin’s lymphoma. Am J Pediatr Hematol Oncol 1983; 5: 27.Google ScholarPubMed
10. Wallace, W H, Thomson, A B, Saran, F, Kelsey, T W. Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int J Radiat Oncol Biol Phys 2005; 62: 738–744.CrossRefGoogle ScholarPubMed
11. Wallace, W H, Thomson, A B, Kelsey, T W. The radiosensitivity of the human oocyte. Hum Reprod 2003; 18: 117–121.CrossRefGoogle ScholarPubMed