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Five- and ten-year survival of squamous cell carcinoma of the head and neck in northern Thailand: a multivariate analysis

Published online by Cambridge University Press:  13 August 2020

Somvilai Chakrabandhu ,
Walaithip Bunyatisai Open the ORCID record for Walaithip Bunyatisai [Opens in a new window] ,
Patumrat Sripan ,
Patrinee Traisathit  and
Imjai Chitapanarux
Somvilai Chakrabandhu
Affiliation:
Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Walaithip Bunyatisai*
Affiliation:
Data Science Research Center, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
Patumrat Sripan
Affiliation:
Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand
Patrinee Traisathit
Affiliation:
Data Science Research Center, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand Center of Excellence in Bioresources for Agriculture, Industry and Medicine, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
Imjai Chitapanarux
Affiliation:
Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Chiang Mai Cancer Registry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
*
Author for correspondence: Walaithip Bunyatisai, Data Science Research Center, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai50200, Thailand. Tel: +6653943381-5. E-mail: walaithip.bun@gmail.com
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Abstract

Aim:

To report 5- and 10-year overall survival (OS) outcomes of squamous cell carcinoma of the head and neck and identify prognostic factors.

Methods:

Data on 2,095 patients at Maharaj Nakorn Chiang Mai Hospital, Thailand between 2007 and 2014 were analysed using the Kaplan–Meyer method to estimate 5- and 10-year OS rates. Cox proportional hazard regression models were applied to assess the independent prognostic factors of survival.

Results:

8·7% had hypopharyngeal cancer, 19·7% laryngeal, 53·3% oral cavity and 18·3% oropharyngeal. Two-thirds of the patients had locally advanced stage (III–IVB). Five- and ten-year OS rates were 30·1 and 22·8%, respectively.

Conclusions:

Cancer site, stage and age at diagnosis were associated with mortality, highlighting the importance of prevention and early detection.

Keywords

epidemiologyhead and neck cancersprognosissurvivalThailand
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 20 , Issue 4 , December 2021 , pp. 413 - 418
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Copyright
© The Author(s), 2020. Published by Cambridge University Press

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