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Five- and ten-year survival of squamous cell carcinoma of the head and neck in northern Thailand: a multivariate analysis

Published online by Cambridge University Press:  13 August 2020

Somvilai Chakrabandhu ,
Walaithip Bunyatisai Open the ORCID record for Walaithip Bunyatisai [Opens in a new window] ,
Patumrat Sripan ,
Patrinee Traisathit  and
Imjai Chitapanarux
Somvilai Chakrabandhu
Affiliation:
Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Walaithip Bunyatisai*
Affiliation:
Data Science Research Center, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
Patumrat Sripan
Affiliation:
Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand
Patrinee Traisathit
Affiliation:
Data Science Research Center, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand Center of Excellence in Bioresources for Agriculture, Industry and Medicine, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
Imjai Chitapanarux
Affiliation:
Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Chiang Mai Cancer Registry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
*
Author for correspondence: Walaithip Bunyatisai, Data Science Research Center, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai50200, Thailand. Tel: +6653943381-5. E-mail: walaithip.bun@gmail.com
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Abstract

Aim:

To report 5- and 10-year overall survival (OS) outcomes of squamous cell carcinoma of the head and neck and identify prognostic factors.

Methods:

Data on 2,095 patients at Maharaj Nakorn Chiang Mai Hospital, Thailand between 2007 and 2014 were analysed using the Kaplan–Meyer method to estimate 5- and 10-year OS rates. Cox proportional hazard regression models were applied to assess the independent prognostic factors of survival.

Results:

8·7% had hypopharyngeal cancer, 19·7% laryngeal, 53·3% oral cavity and 18·3% oropharyngeal. Two-thirds of the patients had locally advanced stage (III–IVB). Five- and ten-year OS rates were 30·1 and 22·8%, respectively.

Conclusions:

Cancer site, stage and age at diagnosis were associated with mortality, highlighting the importance of prevention and early detection.

Keywords

epidemiologyhead and neck cancersprognosissurvivalThailand
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 20 , Issue 4 , December 2021 , pp. 413 - 418
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Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

Jemal, A, Bray, F, Center, M M, Ferlay, J, Ward, E, Forman, D. Global cancer statistics. CA Cancer J Clin 2011; 61 (2): 69–90.CrossRefGoogle ScholarPubMed
Bray, F, Ferlay, J, Soerjomataram, I, Siegel, R L, Torre, LA, Jemal, A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68 (6): 394–424.CrossRefGoogle ScholarPubMed
Mehanna, H, Paleri, V, West, C M L, Nutting, C. Head and neck cancer—Part 1: epidemiology, presentation, and prevention. BMJ 2010; 341: c4684. doi: 10.1136/bmj.c4684.CrossRefGoogle ScholarPubMed
Gupta, B, Johnson, N W, Kumar, N. Global epidemiology of head and neck cancers: a continuing challenge. Oncology 2016; 91 (1): 13–23. doi: 10.1159/000446117.CrossRefGoogle ScholarPubMed
Reyes-Gibby, C C, Anderson, K O, Merriman, K W, Todd, K H, Shete, S S, Hanna, E E. Survival patterns in squamous cell carcinoma of the head and neck: pain as an independent prognostic factor for survival. J Pain 2014; 15 (10): 1015–1022.CrossRefGoogle ScholarPubMed
Kumar, R, Rai, A K, Das, D, et al. Alcohol and tobacco increases risk of high risk HPV Infection in head and neck cancer patients: study from north-east region of India. PLoS One 2015; 10 (10): e0140700. doi: 10.1371/journal.pone.0140700.CrossRefGoogle ScholarPubMed
Ingarfield, K, McMahon, AD, Douglas, CM, Savage, SA, Conway, DI, MacKenzie, K. Determinants of long-term survival in a population-based cohort study of patients with head and neck cancer from Scotland. Head Neck 2019; 41 (6): 1908–1917.CrossRefGoogle Scholar
Reichart, PA, Philipsen, HP, Mohr, U, Geerlings, H, Srisuwan, S. Miang chewing in northern Thai villagers. Trop Geogr Med 1988; 40 (1): 39–44.Google ScholarPubMed
Chen, YJ, Chang, JT, Liao, CT, et al. Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesis. Cancer Sci 2008; 99 (8): 1507–1514. doi: 10.1111/j.1349-7006.2008.00863.x.CrossRefGoogle ScholarPubMed
Liao, CT, Wallace, CG, Lee, LY, et al. Clinical evidence of field cancerization in patients with oral cavity cancer in a betel quid chewing area. Oral Oncol 2014; 50 (8): 721–31. doi: 10.1016/j.oraloncology.2014.04.010.CrossRefGoogle Scholar
Ang, KK, Harris, J, Wheeler, R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010; 363 (1): 24–35. doi: 10.1056/NEJMoa0912217.CrossRefGoogle ScholarPubMed
Boscolo-Rizzo, P, Del Mistro, A, Bussu, F, et al. New insights into human papillomavirus-associated head and neck squamous cell carcinoma. Acta Otorhinolaryngol Ital 2013; 33 (2): 77–87.Google ScholarPubMed
D’Souza, G, Anantharaman, D, Gheit, T, et al. Effect of HPV on head and neck cancer patient survival, by region and tumor site: a comparison of 1362 cases across three continents. Oral Oncol 2016; 62: 20–27. doi: 10.1016/j.oraloncology.2016.09.005.CrossRefGoogle ScholarPubMed
Li, X, Di, B, Shang, Y, Zhou, Y, Cheng, J, He, Z. Clinicopathologic risk factors for distant metastases from head and neck squamous cell carcinomas. Eur J Surg Oncol 2009; 35: 1348–1353.CrossRefGoogle ScholarPubMed
Pruegsanusak, K, Peeravut, S, Leelamanit, V, et al. Survival and prognostic factors of different sites of head and neck cancer: an analysis from Thailand. Asian Pac J Cancer Prev 2012; 13 (3): 885–890.CrossRefGoogle ScholarPubMed
Abrahão, R, Anantharaman, D, Gaborieau, V, et al. The influence of smoking, age and stage at diagnosis on the survival after larynx, hypopharynx and oral cavity cancers in Europe: the ARCAGE study. Int J Cancer 2018; 143 (1): 32–44. doi: 10.1002/ijc.31294.CrossRefGoogle ScholarPubMed
Tiwana, MS, Wu, J, Hay, J, Wong, F, Cheung, W, Olson, RA. 25 year survival outcomes for squamous cell carcinomas of the head and neck: population-based outcomes from a Canadian province. Oral Oncol 2014; 50 (7): 651–656. doi: 10.1016/j.oraloncology.2014.03.009.CrossRefGoogle ScholarPubMed
Cadoni, G, Giraldi, L, Petrelli, L, et al. Prognostic factors in head and neck cancer: a 10-year retrospective analysis in a single-institution in Italy. Acta Otorhinolaryngol Ital 2017; 37 (6): 458–466.CrossRefGoogle Scholar
Laramore, GE, Scott, CB, al-Sarraf, M, et al. Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: report on Intergroup Study 0034. Int J Radiat Oncol Biol Phys 1992; 23 (4): 705–713.CrossRefGoogle ScholarPubMed
Pulte, D, Brenner, H. Changes in survival in head and neck cancers in the late 20th and early 21st century: a period analysis. Oncologist 2010; 15 (9): 994–1001. doi: 10.1634/theoncologist.2009-0289.CrossRefGoogle ScholarPubMed
Lefebvre, JL, Coche-Dequeant, B, Buisset, E, Mirabel, X, Van, JT, Prevost, B. Management of early oral cavity cancer. Experience of Centre Oscar Lambret. Eur J Cancer B Oral Oncol 1994; 30B (3): 216–220.CrossRefGoogle ScholarPubMed
National Comprehensive Cancer Network. Clinical Practice Guidelines in Oncology. Head and Neck Cancer v1. 2018. https://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site. Accessed on 10th January, 2019.Google Scholar
Moskovitz, J, Moy, J, Ferris, RL. Immunotherapy for head and neck squamous cell carcinoma. Curr Oncol Rep 2018; 20 (2): 22. doi: 10.1007/s11912-018-0654-5.CrossRefGoogle ScholarPubMed
Prakash Saxena, PU, Unnikrishnan, B, Rathi, P, Kotian, H, Reshmi, B. Survival analysis of head and neck cancer: results from a hospital based cancer registry in southern Karnataka. Clin Epidemiol Glob Health 2018; 7 (3): 346–350.CrossRefGoogle Scholar
Yeole, BB, Ramanakumar, AV, Sankaranarayanan, R. Survival from oral cancer in Mumbai (Bombay), India. Cancer Causes Control 2003; 14 (10): 945–952.CrossRefGoogle ScholarPubMed
Razak, AA, Saddki, N, Naing, NN, Abdullah, N. Oral cancer survival among Malay patients in Hospital Universiti Sains Malaysia, Kelantan. Asian Pac J Cancer Prev 2010; 11 (1): 187–191.Google ScholarPubMed
Oliveira, ML, Wagner, VP, Sant’ana Filho, M, Carrard, VC, Hugo, FN, Martins, MD. A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay. Braz Oral Res 2015; 29 (1): 1–8. doi: 10.1590/1807-3107BOR-2015.vol29.0075.Google ScholarPubMed
Nandakumar, A, Rath, G, Kataki, A, et al. Survival in head and neck cancers – results of a multi-institution study. Asian Pac J Cancer Prev 2016; 17 (4): 1745–1754.CrossRefGoogle ScholarPubMed
Chitapanarux, I, Traisathit, P, Komolmalai, N, et al. Ten-year outcome of different treatment modalities for squamous cell carcinoma of oral cavity. Asian Pac J Cancer Prev 2017; 18: 1919–1924.Google ScholarPubMed
Kowalski, LP, Carvalho, AL. Natural history of untreated head and neck cancer. Eur J Cancer 2000; 36 (8): 1032–1037.CrossRefGoogle ScholarPubMed
Khuhaprema, T, Srivatanakul, P, Attasara, P, Sriplung, H, Wiangnon, S, Sumitsawan, Y. Cancer In Thailand, Vol. V, 2001–2003. Bangkok, Thailand: Bangkok Medical Publisher, 2010.Google Scholar
Imsamran, W, Chaiwerawattana, A, Wiangnon, S, et al. Cancer In Thailand, Vol. VIII, 2010–2012. Bangkok, Thailand: New Thammada Press (Thailand) Co., Ltd., 2015.Google Scholar
World Health Organization. The ICD-10 classification of neoplasm: clinical descriptions and diagnostic guidelines. Geneva, Switzerland: WHO Press, 2010.Google Scholar
Edge, S, Byrd, DR, Compton, CC, Friz, AG, et al. AJCC Cancer Staging Manual, 7th edition. New York: Springer-Verlag, 2010.Google ScholarPubMed
Mickey, RM and Greenland, S. The impact of confounder selection criteria on effect estimation. Am J Epidemiol 1989; 129 (1): 125–137.CrossRefGoogle ScholarPubMed
Gatta, G, Botta, L, Sánchez, MJ, et al. Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: the EUROCARE-5 population-based study. Eur J Cancer 2015; 51 (15): 2130–2143. doi: 10.1016/j.ejca.2015.07.043.CrossRefGoogle ScholarPubMed
Milisavljevic, D, Stankovic, M, Zivic, M, Popovic, M, Radovanović, Z. Factors affecting results of treatment of Hypopharyngeal Carcinoma. Hippokratia 2009; 13 (3): 154–160.Google ScholarPubMed
Short, PF, Vasey, JJ, Tunceli, K. Employment pathways in a large cohort of adult cancer survivors. Cancer 2005; 103: 1292–301.CrossRefGoogle Scholar
Chen, AY, Matson, LK, Roberts, D, Goepfert, H. The significance of comorbidity in advanced laryngeal cancer. Head Neck 2001; 23 (7): 566–572.CrossRefGoogle ScholarPubMed
de Cássia Braga Ribeiro, K, Kowalski, LP, Latorre Mdo, R. Perioperative complications, comorbidities, and survival in oral or oropharyngeal cancer. Arch Otolaryngol Head Neck Surg 2003; 129 (2): 219–228.CrossRefGoogle ScholarPubMed